Fig. 5 | Scientific Reports

Fig. 5

From: Identification and validation of inflammatory response genes linking chronic kidney disease with coronary artery disease based on bioinformatics and machine learning

Fig. 5

The integration of CKD datasets and identification of IRGGs in CKD related CAD. (A, B) PCA plots of two CKD datasets before and after batch-effect correction. (C) The volcano plot showing DEGs of integrated CKD dataset. Upregulated gene were represented by red dots, while downloaded genes were represented by bule dots. (D) The heatmap presenting the top 20 upregulated and 20 downregulated DEGs of integrated CKD dataset. (E) The intersection of key genes in CKD related CAD and IRGGs through venn diagram. CKD, chronic kidney disease; IRGGs, inflammatory response-related genes; CAD, coronary artery disease; DEGs, differentially expressed genes; PCA, principal component analysis.

Back to article page