Fig. 9 | Scientific Reports

Fig. 9

From: Identification and validation of inflammatory response genes linking chronic kidney disease with coronary artery disease based on bioinformatics and machine learning

Fig. 9

Validation of the expression patterns of three hub genes in CKD patients and assessment of their diagnostic value for CAD in this population. (A–C) Expression levels of three hub genes from hemodialysis patients with or without CAD. (D, E) ROC curve of diagnostic performance including GCLM and NUPR1 in hemodialysis patients. (F, H) Expression levels of three hub genes from patients with CKD stage 3–5 with or without CAD. (I, J) The ROC curve of diagnostic performance including GCLM and NUPR1 in patients with CKD stage 3–5. CKD, chronic kidney disease; CAD, coronary artery disease. *p < 0.05; **p < 0.01; ***p < 0.001; ns not significant.

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