Table 3 The comparison of laboratory parameters in active stage vs non-active stage.
pSS | |||
|---|---|---|---|
Active stage (ESSDAI ≥ 5) | Non-active stage (ESSDAI < 5) | P value | |
Number | 119 | 32 | |
Gender (Female/male) | 113/6 | 32/0 | 0.432 |
Age | 54.1 ± 13.9 | 45.6 ± 10.3 | 0.001** |
GDF15, pg/mL | 1423 (934–2674) | 821 (632–1078) | < 0.001*** |
Total protein, g/L | 71.8 (66.1–79.4) | 76.4 (70.7–80) | 0.062 |
Albumin, g/L | 39.5 (35.6–43.1) | 45.3 (43.5–47.2) | < 0.001*** |
Globulin, g/L | 32.8 (28.5–37.3) | 30.5 (26.5–33.7) | 0.035* |
Albumin/Glbumin | 1.2 (1–1.4) | 1.5 (1.4–1.7) | < 0.001*** |
C-reactive protein, mg/L | 3.2 (1.9–7.7) | 1.7 (1.3–1.9) | < 0.001*** |
Erythrocyte sedimentation rate, mm/h | 62 (34.8–94.5) | 26 (17–66) | 0.001** |
Rheumatoid factor, IU/ ml | 32.4 (20–100) | 24.4 (20–86.5) | 0.437 |
Complement fractions 4, mg/L | 195 (148.5–234) | 181.5 (142.5–216) | 0.505 |
Complement fractions 3, mg/L | 819 (682–962.5) | 859.5 (777–932) | 0.303 |
Immunoglobulins G, g/L | 18.1 (13.5–21.9) | 14.7 (13.4–18.2) | 0.056 |
Immunoglobulins A, mg/L | 3170 (2440–4205) | 2885 (1925–3651) | 0.165 |
Immunoglobulins M, mg/L | 1170 (838–1560) | 1295 (982–1860) | 0.196 |
White blood cell count, × 109/L | 5.5 (4.5–7.1) | 5.3 (4.4–5.9) | 0.164 |
Neutrophil count, × 109/L | 3.6 (2.4–5.3) | 3.1 (2.4–3.7) | 0.065 |
Red blood cell count, × 1012/L | 4.1 (3.7–4.3) | 4.5 (4.3–4.6) | < 0.001*** |
Haemoglobin, g/L | 119 (108.5–129) | 133 (124–136.5) | < 0.001*** |
Platelet count, × 109/L | 207.5 (150.5–257) | 200 (175–264) | 0.329 |
Positive anti-SSA antibody (%) | 90.2 | 89.7 | 1.0 |
Positive anti-SSB antibody (%) | 50.0 | 34.5 | 0.139 |
Antinuclear antibody positive (%) | 87.5 | 89.7 | 0.932 |
