Table 1 Clinicopathological characteristics of NMIBC patients who underwent RC, stratified by PLND and No-PLND.

From: Impact of pelvic lymph node dissection on survival outcomes in non-muscle invasive bladder cancer: a multicenter retrospective study

Variable

Total

No-PLND

PLND

p value

(n = 544)

(n = 132)

(n = 412)

 

Median age, yr (IQR)

69 (63–75)

69 (64–74)

69 (63–75)

0.760

Gender, n (%)

   

0.942

Female

98 (18.0)

23 (17.4)

75 (18.2)

 

Male

446 (82.0)

109 (82.6)

337 (81.8)

 

Clinical T-stage, n (%)

   

0.593

cTa

16 (2.9)

5 (3.8)

11 (2.7)

 

cTis

19 (3.5)

6 (4.5)

13 (3.2)

 

cT1

509 (93.6)

121 (91.7)

388 (94.2)

 

Tumor grade, n (%)

   

0.466

Low

61 (11.2)

12 (9.1)

49 (11.9)

 

High

483 (88.8)

120 (90.9)

363 (88.1)

 

Concomitant CIS, n (%)

   

0.439

Absent

447 (82.2)

105 (79.5)

342 (83.0)

 

Pesent

97 (17.8)

27 (20.5)

70 (17.0)

 

Lymphovascular invasion, n (%)

   

0.084

Absent

463 (85.1)

119 (90.2)

344 (83.5)

 

Present

81 (14.9)

13 (9.8)

68 (16.5)

 

Histological subtypes, n (%)

   

0.928

Absent

425 (78.1)

104 (78.8)

321 (77.9)

 

Present

119 (21.9)

28 (21.2)

91 (22.1)

 

Pathological T-stage, n (%)

   

0.017*

pT0

44 (8.1)

6 (4.5)

38 (9.2)

 

pTa

3 (0.6)

1 (0.8)

2 (0.5)

 

pTis

32 (5.9)

8 (6.1)

24 (5.8)

 

pT1

272 (50.0)

82 (62.1)

190 (46.1)

 

pT2

113 (20.8)

24 (18.2)

89 (21.6)

 

pT3

61 (11.2)

6 (4.5)

55 (13.3)

 

pT4

19 (3.5)

5 (3.8)

14 (3.4)

 

Median removed lymph nodes (IQR)

-

-

14 (8–21)

-

Pathological N-stage, n (%)

   

-

pN0

383 (70.4)

-

383 (93.0)

 

pN1

19 (3.5)

-

19 (4.6)

 

pN2

10 (1.8)

-

10 (2.4)

 

pNx

132 (24.3)

132 (100.0)

-

 
  1. PLND = Pelvic lymph node dissection; CIS = Carcinoma in situ; * p < 0.05; No p-values were calculated for Pathological N-stage due to the absence of pNx cases in the PLND group and pN0, pN1, pN2 cases in the No-PLND group.