Table 2 Demographic and clinical characteristics of COVID-19 patients.

From: Characteristics of SARS-CoV-2 variants and potential co-infected pathogens in hospitalized patients based on metagenomic next-generation sequencing

  

Non-severe pneumonia (n = 131)

Severe pneumonia (n = 69)

P

Gender

Male

88 (67.18%)

55 (79.71%)

0.0619

Female

43 (32.82%)

14 (20.29%)

Age

Median (years)

68 (58 ~ 78)

74 (65.5 ~ 79)

0.0277

 < 65

51 (38.93%)

15 (21.74%)

0.014

 ≥ 65

80 (61.07%)

54 (78.26%)

Comorbidity

Hypertension

59 (45.04%)

43 (62.32%)

0.0201

Obesity

57 (43.51%)

29 (42.03%)

0.8405

Malignancies

64 (48.85%)

26 (37.68%)

0.1311

Chemotherapy

40 (30.53%)

9 (13.04%)

0.0063

Diabetes mellitus

31 (23.66%)

31 (44.93%)

0.0002

Cardiovascular disease

29 (22.14%)

18 (26.09%)

0.5312

Chronic cardiac disease

23 (17.56%)

17 (26.64%)

0.234

Chronic pulmonary disease

19 (14.5%)

12 (17.39%)

0.5917

Chronic kidney disease

13 (9.92%)

15 (21.74%)

0.0221

Liver disease

13 (9.92%)

9 (13.04%)

0.5027

Rheumatologic disorder

11 (8.4%)

6 (8.7%)

0.9426

Malnutrition

6 (4.58%)

8 (11.59%)

0.1196

Smoking

7 (5.35%)

1 (1.45%)

0.3388

Chronic neurological disorder

4 (3.05%)

4 (5.80%)

0.5743

Chronic haematological disease

3 (2.29%)

1 (1.45%)

1.0000

Tuberculosis

3 (2.29%)

1 (1.45%)

1.0000

Dementia

1 (0.76%)

1 (1.45%)

1.0000

Symptom

Fever

78 (59.54%)

54 (78.26%)

0.0079

Cough

72 (54.96%)

45 (65.22%)

0.1617

Expectoration

54 (41.22%)

33 (47.83%)

0.3704

Shortness of breath

25 (19.08%)

33 (47.83%)

 < 0.0001

Fatigue/malaise

10 (7.63%)

7 (10.14%)

0.5449

Muscle aches/joint pain

9 (6.87%)

5 (7.25%)

1.0000

Vomiting/nausea

12 (9.16%)

3 (4.35%)

0.2193

Headache

7 (5.34%)

5 (7.25%)

0.8261

Pulmonary shadow

6 (4.58%)

0 (0%)

0.0952

Diarrhoea

3 (2.29%)

2 (2.9%)

1.0000

Abdominal pain

1 (0.76%)

2 (2.9%)

0.2739

Altered consciousness/confusion

1 (0.76%)

2 (2.9%)

0.2739

Radiology

Pleural effusion

23 (17.56%)

34 (49.28%)

 < 0.0001

Exudation

14 (10.69%)

25 (36.23%)

 < 0.0001

Patchy/ground-glass opacity

85 (64.89%)

60 (86.96%)

0.0009

Pulmonary nodule

79 (60.31%)

23 (33.33%)

0.0003

Complete blood count

Leukocyte (109/L)

7.16 (6.43 to 7.90)

9.69 (8.19 to 11.19)

0.0033

Neutrophil (109/L)

5.41 (4.67 to 6.18)

8.65 (7.26 to 10.04)

 < 0.0001

Lymphocyte (109/L)

1.61 (0.61 to 2.61)

0.611 (0.38 to 0.84)

0.0550

Physical examination

Heart rate

87.47 (84.29 to 90.64)

91.36 (87.27 to 95.45)

0.1451

Systolic blood pressure

125.40 (121.80 to 128.90)

139.80 (133.70 to 145.90)

 < 0.0001

Diastolic blood pressure

73.93 (71.73 to 76.13)

76.99 (74.33 to 79.64)

0.0931

Respiratory rate

19.60 (19.19 to 20.02)

21.28 (20.04 to 22.51)

0.0123