Table 2 Demographic and clinical characteristics of COVID-19 patients.
Non-severe pneumonia (n = 131) | Severe pneumonia (n = 69) | P | ||
---|---|---|---|---|
Gender | Male | 88 (67.18%) | 55 (79.71%) | 0.0619 |
Female | 43 (32.82%) | 14 (20.29%) | ||
Age | Median (years) | 68 (58 ~ 78) | 74 (65.5 ~ 79) | 0.0277 |
< 65 | 51 (38.93%) | 15 (21.74%) | 0.014 | |
≥ 65 | 80 (61.07%) | 54 (78.26%) | ||
Comorbidity | Hypertension | 59 (45.04%) | 43 (62.32%) | 0.0201 |
Obesity | 57 (43.51%) | 29 (42.03%) | 0.8405 | |
Malignancies | 64 (48.85%) | 26 (37.68%) | 0.1311 | |
Chemotherapy | 40 (30.53%) | 9 (13.04%) | 0.0063 | |
Diabetes mellitus | 31 (23.66%) | 31 (44.93%) | 0.0002 | |
Cardiovascular disease | 29 (22.14%) | 18 (26.09%) | 0.5312 | |
Chronic cardiac disease | 23 (17.56%) | 17 (26.64%) | 0.234 | |
Chronic pulmonary disease | 19 (14.5%) | 12 (17.39%) | 0.5917 | |
Chronic kidney disease | 13 (9.92%) | 15 (21.74%) | 0.0221 | |
Liver disease | 13 (9.92%) | 9 (13.04%) | 0.5027 | |
Rheumatologic disorder | 11 (8.4%) | 6 (8.7%) | 0.9426 | |
Malnutrition | 6 (4.58%) | 8 (11.59%) | 0.1196 | |
Smoking | 7 (5.35%) | 1 (1.45%) | 0.3388 | |
Chronic neurological disorder | 4 (3.05%) | 4 (5.80%) | 0.5743 | |
Chronic haematological disease | 3 (2.29%) | 1 (1.45%) | 1.0000 | |
Tuberculosis | 3 (2.29%) | 1 (1.45%) | 1.0000 | |
Dementia | 1 (0.76%) | 1 (1.45%) | 1.0000 | |
Symptom | Fever | 78 (59.54%) | 54 (78.26%) | 0.0079 |
Cough | 72 (54.96%) | 45 (65.22%) | 0.1617 | |
Expectoration | 54 (41.22%) | 33 (47.83%) | 0.3704 | |
Shortness of breath | 25 (19.08%) | 33 (47.83%) | < 0.0001 | |
Fatigue/malaise | 10 (7.63%) | 7 (10.14%) | 0.5449 | |
Muscle aches/joint pain | 9 (6.87%) | 5 (7.25%) | 1.0000 | |
Vomiting/nausea | 12 (9.16%) | 3 (4.35%) | 0.2193 | |
Headache | 7 (5.34%) | 5 (7.25%) | 0.8261 | |
Pulmonary shadow | 6 (4.58%) | 0 (0%) | 0.0952 | |
Diarrhoea | 3 (2.29%) | 2 (2.9%) | 1.0000 | |
Abdominal pain | 1 (0.76%) | 2 (2.9%) | 0.2739 | |
Altered consciousness/confusion | 1 (0.76%) | 2 (2.9%) | 0.2739 | |
Radiology | Pleural effusion | 23 (17.56%) | 34 (49.28%) | < 0.0001 |
Exudation | 14 (10.69%) | 25 (36.23%) | < 0.0001 | |
Patchy/ground-glass opacity | 85 (64.89%) | 60 (86.96%) | 0.0009 | |
Pulmonary nodule | 79 (60.31%) | 23 (33.33%) | 0.0003 | |
Complete blood count | Leukocyte (109/L) | 7.16 (6.43 to 7.90) | 9.69 (8.19 to 11.19) | 0.0033 |
Neutrophil (109/L) | 5.41 (4.67 to 6.18) | 8.65 (7.26 to 10.04) | < 0.0001 | |
Lymphocyte (109/L) | 1.61 (0.61 to 2.61) | 0.611 (0.38 to 0.84) | 0.0550 | |
Physical examination | Heart rate | 87.47 (84.29 to 90.64) | 91.36 (87.27 to 95.45) | 0.1451 |
Systolic blood pressure | 125.40 (121.80 to 128.90) | 139.80 (133.70 to 145.90) | < 0.0001 | |
Diastolic blood pressure | 73.93 (71.73 to 76.13) | 76.99 (74.33 to 79.64) | 0.0931 | |
Respiratory rate | 19.60 (19.19 to 20.02) | 21.28 (20.04 to 22.51) | 0.0123 |