Table 3 Logistic regression analysis of factors associated with severe-pneumonia of COVID-19 patients.

From: Characteristics of SARS-CoV-2 variants and potential co-infected pathogens in hospitalized patients based on metagenomic next-generation sequencing

Parameter

Univariate analysis

Multivariate analysis

OR (95%CI)a

P value

OR (95%CI)a

P value

Age

    

  < 65

Reference value

   

  >  = 65

2.295 (1.173, 4.491)

0.015

1.721 (0.813,3.643)

0.156

Gender

 Male

Reference value

   

 Female

1.920 (0.926, 3.830)

0.064

  

Comorbidity

 Hypertension

2.018 (1.112, 3.664)

0.021

1.184 (0.591, 2.370)

0.634

 Obesity

0.941 (0.522, 1.698)

0.840

  

 Malignancies

0.633 (0.349, 1.148)

0.132

  

 Chemotherapy

0.341 (0.154, 0.754)

0.341

  

 Diabetes mellitus

2.632 (1.412, 4.904)

0.002

2.033 (1.029, 4.015)

0.041

 Cardiovascular disease

1.241 (0.631, 2.444)

0.532

  

 Chronic cardiac disease

1.535 (0.756, 3.119)

0.236

  

 Chronic pulmonary disease

1.241 (0.563, 2.734)

0.592

  

 Chronic kidney disease

2.521 (1.122, 5.665)

0.025

2.226 (0.948, 5.224)

0.066

 Liver disease

1.362 (0.551, 3.365)

0.504

  

 Rheumatologic disorder

1.039 (0.367, 2.941)

0.943

  

 Malnutrition

2.731 (0.908, 8.224)

0.074

  

 Smoking

0.261 (0.031, 2.162)

0.213

  

 Chronic neurological disorder

1.954 (0.473, 8.065)

0.354

  

 Chronic haematological disease

0.627 (0.064, 6.148)

0.689

  

 Tuberculosis

0.627 (0.064, 6.148)

0.689

  

 Dementia

1.912 (0.118, 31.041)

0.649

  
  1. aOR odds ratio, CI confidence interval.