Table 2 OCT findings according to the severity of area stenosis.
From: Plaque vulnerability and thrombus formation according to area stenosis in chronic stable angina
Group A Area stenosis < 50% (24 lesions) | Group B 50% ≤ Area stenosis < 70% (51 lesions) | Group C Area stenosis ≥ 70% (99 lesions) | P value | |
|---|---|---|---|---|
Target coronary artery | 0.675 | |||
Left anterior descending artery | 16 (66.7) | 34 (66.6) | 70 (70.7) | 0.003 |
Left circumflex artery | 4 (16.7) | 4 (7.8) | 11 (11.1) | 0.228 |
Right coronary artery | 4 (16.7) | 13 (25.5) | 18 (18.2) | 0.039 |
Plaque type | 0.099 | |||
Fibrous plaque | 5 (20.8) | 10 (19.6) | 9 (9.1) | 0.417 |
Lipid-rich plaque | 10 (41.7) | 26 (51.0) | 66 (66.7) | 0.028 |
Fibro-calcific plaque | 9 (37.5) | 15 (29.4) | 24 (24.2) | 0.001 |
Macrophage infiltration | 8 (33.3) | 26 (51.0) | 71 (71.7) | 0.001 |
Calcifications | 15 (62.5) | 32 (62.7) | 72 (72.7) | 0.368 |
Maximal lipid angle, ° | 148.9 ± 79.5 | 189.9 ± 71.0 | 209.0 ± 66.0 | 0.001 |
Longitudinal lipid length, mm | 16.2 ± 6.5 | 15.9 ± 4.9 | 17.8 ± 6.4 | 0.162 |
Minimal cap thickness on fibroatheroma, µm | 119.6 ± 68.1 | 127.7 ± 62.3 | 117.1 ± 55.7 | 0.586 |
Thin cap fibroatheroma (< 65 µm) | 2 (8.3) | 5 (9.8) | 16 (16.2) | 0.414 |
Minimal cap thickness on calcification, µm | 77.9 ± 39.9 | 77.5 ± 33.2 | 69.2 ± 31.0 | 0.251 |
Thin cap calcified plaque (< 65 µm) | 5 (20.8) | 14 (27.5) | 51 (51.5) | 0.002 |
Multi-layered plaque | 15 (62.5) | 33 (64.7) | 67 (67.7) | 0.868 |
Microchannel | 14 (58.3) | 27 (52.9) | 45 (45.5) | 0.441 |
Lumen irregularity | 2 (8.3) | 12 (23.5) | 37 (37.4) | 0.011 |
Ruptured plaque | 0 | 8 (15.7) | 25 (25.3) | 0.014 |
Location of ruptured plaque | 0.925 | |||
Proximal | 0 | 1 (12.5) | 2 (8.0) | |
Minimal lumen area site | 0 | 6 (75.0) | 0 (80.0) | |
Distal | 0 | 1 (12.5) | 3 (12.0) | |
Thrombus | 0 | 9 (17.6) | 24 (24.2) | 0.024 |
Thrombus with lumen irregularity | 0 | 6 (11.8) | 17 (17.2) | 0.078 |
Thrombus with ruptured plaque | 0 | 3 (5.9) | 12 (12.1) | 0.117 |
Location of thrombus | 0.636 | |||
Proximal | 0 | 3 (22.2) | 4 (16.7) | |
Minimal lumen area site | 0 | 4 (44.5) | 15 (62.5) | |
Distal | 0 | 3 (33.3) | 5 (20.8) | |
Thrombus type | 0.112 | |||
Red thrombus | 0 | 5 (9.8) | 14 (14.1) | 0.039 |
White thrombus | 0 | 4 (7.8) | 10 (10.1) | 0.109 |
Size of thrombus | ||||
Area, mm2 | 0 | 0.02 ± 0.05 | 0.05 ± 0.20 | 0.212 |
Maximal diameter, mm | 0 | 0.08 ± 0.21 | 0.14 ± 0.32 | 0.051 |
Minimal diameter, mm | 0 | 0.04 ± 0.10 | 0.06 ± 0.15 | 0.079 |
Lesion length, mm | 18.9 ± 6.8 | 17.5 ± 5.2 | 19.1 ± 6.4 | 0.297 |
Minimal lumen area, mm2 | 4.8 ± 2.0 | 3.0 ± 1.3 | 1.6 ± 0.8 | < 0.001 |
Area stenosis, % | 40.8 ± 6.6 | 61.6 ± 5.8 | 80.0 ± 5.7 | < 0.001 |
