Table 1 Animal experiments used for mechanistic model evaluation.
From: Mathematical mechanistic model representing the cancer immunity cycle under radiation effects
No | Tumor cells | Secondary tumor | Radiation | Drug | Data set | |
|---|---|---|---|---|---|---|
Primary tumor | DLN | |||||
1 | MC38 | No | - | – | aPD-L1, aCD8, | Chamoto et al.17 |
2 | aPD-L1, Bezafibrate | |||||
3 | TSA | Yes | 8 Gy x 3 | – | aCTLA4 | V-Box et al.22 |
4 | 20 Gy x 1 | – | aCTLA4 | |||
5 | B16F10 | Yes | 10 Gy x 1 | 3 Gy x 3 | – | Buchwald et al.20 |
6 | MC38-OVA | No | 12Â Gy x 1 | 12Â Gy x 1 | aPD-1, aCTLA-4 | Marciscano et al.21 |
7 | B16-OVA | Yes | 15 Gy x 1 | – | aPD-1 | Park et al.31 |
8 | MC38 | No | 16 Gy x 1 | – | aPD-1 | Moore et al.32 |
9 | 8 Gy x 2 | – | aPD-1 | |||
10 | LLC | No | 10 Gy x 2 | – | aPD-1 | |
