Table 3 MRI finding of the two groups of patients. SD: standard deviation; SEGA: subependymal giant cell astrocytoma.
TSC1 patients | TSC2 patients | p value | |
---|---|---|---|
Tubers | |||
Absence of tubers | 5 (16%) | 5 (10%) | NS |
1 to 5 tubers | 5 (16.1%) | 7 (14%) | NS |
More than 5 tubers | 21 (67.8%) | 36 (72%) | NS |
Mean size of tubers (SD) | 8 mm (3.9) | 17 mm (18.3) | < 0.01 |
Tubers dimensions range (95% C.I.) | 5–20 mm | 4–30 mm | NS |
Subependymal nodules | |||
Absence of subependymal nodules | 5(16.1%) | 11(22%) | NS |
1 to 5 subependymal nodules | 10(32.3%) | 2(4%) | NS |
More than 5 subependymal nodules | 16(51.6%) | 31(62%) | NS |
Average size of subependymal nodules (SD) | 3.87 mm (2.09) | 9.4 mm (0.9) | < 0.01 |
Subependymal nodules dimensions range (95% C.I.) | 2–10 mm | 5–12 mm | NS |
Subependymal giant-cell astrocytomas | |||
Patients without SEGA | 29 (93.6%) | 43 (86%) | NS |
1 SEGA | 2 (6.4%) | 6 (12%) | NS |
2 or more SEGA | 0 | 1 (2%) | NS |
Patients underwent SEGA surgery | 1 (50%) | 4 (57%) | NS |
Average size Of SEGAs (SD) | 1.1 cm (0.2) | 1.3 cm (0.15) | NS |
SEGA dimensions range (95% C.I.) | 1–1.2 cm | 1–1.5 cm | NS |
Radial bands | |||
Presence of radial bands | 12 (38.7%) | 6 (12%) | 0.011 |
1 radial band | 3 (9.7%) | 2 (4%) | NS |
2 or more radial bands | 9 (29%) | 4 (8%) | 0.028 |
Cerebral cysts | |||
Absence of cerebral cysts | 30 (96.7%) | 47 (94%) | NS |
1 cerebral cyst | 0 | 2 (4%) | NS |
2 or more cerebral cysts | 1 (3.2%) | 1 (2%) | NS |
White matter abnormalities | |||
Absence of white matter abnormalities | 22 (71%) | 37 (74%) | NS |
Limited white matter abnormalities | 4 (12.9%) | 5 (10%) | NS |
Diffuse white matter abnormalities | 5 (16.1%) | 8 (16%) | NS |