Table 3 Analysis of variance for response surface quadratic model of entrapment efficiency.

From: Preparation and property evaluation of oral colon targeted protein delivery system with sodium alginate and chitosan

Source

Sum of Squares

df

Mean Square

F-value

p-value

Model

161.88

14

11.56

31.29

< 0.0001

A-Sodium alginate

1.76

1

1.76

4.77

0.0464

B-CaCl2

12.85

1

12.85

34.79

< 0.0001

C-Chitosan

31.20

1

31.20

84.45

< 0.0001

D-stirring time

3.13

1

3.13

8.48

0.0114

AB

2.50

1

2.50

6.76

0.0210

AC

6.81

1

6.81

18.44

0.0007

AD

14.52

1

14.52

39.29

< 0.0001

BC

1.37

1

1.37

3.70

0.0748

BD

0.3364

1

0.3364

0.9105

0.3562

CD

0.0650

1

0.0650

0.1760

0.6812

A²

50.33

1

50.33

136.22

< 0.0001

B²

13.09

1

13.09

35.43

< 0.0001

C²

42.90

1

42.90

116.12

< 0.0001

D²

23.46

1

23.46

63.50

< 0.0001

Residual

5.17

14

0.3695

  

Lack of Fit

4.04

10

0.4036

1.42

0.3930

Pure Error

1.14

4

0.2841

  

Cor Total

167.05

28

   
  1. Notes: P-value < 0.05 indicates that the model or factors have significant influence of the model, while P-value < 0.01 indicates an extremely significant effect of the model.
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