Fig. 1

RBM47 functions as a tumor suppressor in colorectal cancer. (A) Box plot showing the expression level of RBM47 in tumor and adjacent normal tissues of COAD patients from TCGA. (B) The survival curve of RBM47 in colorectal cancer in TCGA. (C) The histogram showed the RT-qPCR results of control and treatment samples. *** P-value < 0.001. (D) The result of western blot experiment showed that the RBM47 over expression was successful. (E) The proliferation results of HTC116 after RBM47 overexpression. * P-value < 0.05; ** P-value < 0.01. (F) The apoptosis results of HTC116 after RBM47 overexpression. *** P-value < 0.001. (G) The invasion results of HCT116 cells after RBM47 overexpression. ** P-value < 0.01. (H) The migration results of HCT116 cells after RBM47 overexpression. *** P-value < 0.001.