Table 2 GO, KEGG, and human protein atlas enrichment analyses.

From: Discovering molecular signatures in kidney transplant biopsies with borderline changes and isolated V-lesions: single-cell RNA-sequencing analysis of human blood and tissue Spatial transcriptomics

(A) pre-TCMR(p) vs. TCMR(p)

Chart color

P-value

Precision

Query size

Recall

Source

Term ID

Term name

Term size

Sky blue

1.36E − 05

0.26087

23

0.041379

Gene Ontology Biological Process

GO:0034341

Response to type II interferon

145

Blue

2.43E − 05

0.263158

19

0.072464

KEGG

KEGG:04612

Antigen processing and presentation

69

Yellow green

1.72E − 04

0.263158

19

0.04902

KEGG

KEGG:04064

NF-κB signaling pathway

102

Green

1.79E − 04

0.26087

23

0.021583

Gene Ontology Molecular Function

GO:0005123

Cytokine receptor binding

278

Pink

2.92E − 04

0.521739

23

0.006166

Gene Ontology Biological Process

GO:0006955

Immune response

1946

(B) post-CTRL(p) vs. TCMR(p)

Chart color

P-value

Precision

Recall

Source

Term ID

Term name

Term size

 

Sky blue

1.22E − 11

0.853659

0.017851

Human Protein Atlas

HPA:0530000

Spleen

5882

 

Blue

6.07E − 11

0.861789

0.017357

Human Protein Atlas

HPA:0600441

Tonsil; non-germinal center cells

6107

 

Yellow green

1.73E − 10

0.796748

0.018414

Human Protein Atlas

HPA:0530711

Spleen; cells in red pulp

5322

 

Green

4.61E − 09

0.658537

0.020347

Human Protein Atlas

HPA:0310442

Lymph node; non-germinal center cells

3981

 

Pink

1.18E − 08

0.829268

0.016851

Human Protein Atlas

HPA:0310441

Lymph node; non-germinal center cells

6053

 
  1. GO gene ontology, KEGG Kyoto encyclopedia of genes and genomes, HPA human protein atlas, TCMR acute T cell-mediated rejection.
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