Fig. 1
From: Low expression of SGCA promotes lung squamous cell carcinoma malignant progression

Screening for SGCA in the TCGA database and LUSC patient tissues. (A) 3348 DEGs in LUSC and normal group, and 2085 DEGs were upregulated and 1263 genes were downregulated in LUSC group; (B) Expression of SGCA in LUSC and normal group in TCGA; (C) ROC curve to assess the diagnostic significance of SGCA; (D) Survival curves were used to assess the prognostic significance of SGCA; (E) GO and KEGG enrichment analysis and select the top 12 pathways with high correlation with SGCA; (F) Enrichment plots from GSEA; (G) Expression of SGCA in LUSC and normal group in LUSC patient tissues; (H) Cross-sections of adjacent tissues were SGCA stained; (I) Cross-sections of low SGCA expression groups tumor tissues were SGCA stained; (J) Cross-sections of high SGCA expression groups tumor tissues were SGCA stained; (K) Cross-sections of low SGCA expression groups tumor tissues were H&E stained; (L) Cross-sections of high SGCA expression groups tumor tissues were H&E stained. GSEA, gene set enrichment analysis; TCGA, The Cancer Genome Atlas; DEGs, differentially expressed genes.