Fig. 2 | Scientific Reports

Fig. 2

From: Low expression of SGCA promotes lung squamous cell carcinoma malignant progression

Fig. 2

SGCA overexpressing attenuates the behaviors of H520 and H1703 cells. (A) The expression of SGCA in BEAS-2B, H520 and H1703 cell; (B) The transfection efficiency of SGCA overexpressing in NSCLC; (C, D) SGCA overexpressing H520 and H1703 cell proliferation and colony formation; (E, F) The migratory and invasive properties of SGCA overexpressing H520 and H1703 cells were determined via Transwell experiments; (G) MMPs expression was measured in SGCA overexpressing-transfected H520 and H1703 cells; (H) BAX, Bcl-2 expression was measured in SGCA overexpressing-transfected H520 and H1703 cells; (I) The level of apoptosis of Wild cells, NC cells and SGCA overexpressing H520 and H1703 cells. Apoptotic cells were labelled with Tunel in green fluorescently labelled phalloidin. The nucleus was stained with DAPI in blue fluorescently labelled phalloidin; (J) Apoptosis of H520 and H1703 cells transfected with the SGCA overexpressing was examined (*p < 0.05; **p < 0.01;***p < 0.001).

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