Table 3 Significant changes of hematological and biochemical parameters before vs after 4 pp and before vs after 8 pp, in male, female, all participants.

From: Human clinical trial of plasmapheresis effects on biomarkers of aging (efficacy and safety trial)

 

Change

pp 4

pp 8

m

f

all

m

f

all

White blood count

-

-

-

-

*

-

Mean corpuscular hemoglobin conc

-

-

-

-

-

*

Mononuclears

-

**

*

**

**

***

Lymphocytes_absolute count

-

-

-

-

*

-

Basosophils_absolute count

-

-

-

-

*

-

Red cell distribution width

-

-

-

**

*

***

Potassium

-

-

-

*

-

*

Calcium

-

**

*

-

**

**

Phosphorus

-

-

-

**

*

***

Total cholesterol

-

*

*

-

**

**

nonHDL

-

*

*

-

**

**

Apolipoprotein A

-

**

***

**

**

***

Apolipoprotein B

-

-

-

-

*

*

Triglycerides

-

**

*

-

**

*

Total proteins

**

***

***

*

**

**

Albumin

*

***

***

*

*

**

C reactive protein

-

-

-

-

*

-

Estrogen

-

-

*

*

-

*

Progesterone

-

-

-

***

-

*

Homocysteine

-

-

-

-

*

**

DHEA

**

-

**

**

-

*

Thyroxin

-

-

-

*

-

-

Granulocyte colony stimulating factor

*

-

*

*

-

-

Vascular endothelial factor A

-

-

-

*

*

**

Vitamin D

**

*

**

***

**

***

  1. Legend: This table presents the statistically significant changes in various blood parameters before versus after 4 plasmapheresis sessions (4 pp) and before versus after 8 plasmapheresis sessions (8 pp) for males (m), females (f), and all participants combined (all). Symbols indicate significance levels (* p < 0.05, ** p < 0.01, *** p < 0.001) and arrows denote the direction of change (↑ for increase, ↓ for decrease). It highlights the specific biological markers that were significantly affected by the plasmapheresis protocol.