Table 3 Predictors of loss analyzed by univariate and multivariate regression.

From: Predictors for quantitative flow ratio loss in patients with de novo coronary artery disease treated with drug-coated balloons

Variables

Univariate regression

Multivariate regression

OR

95%CI

P value

OR

95%CI

P value

Baseline characters

 Male [%]

0.415

0.143–1.207

0.107

   

 Age > 65 years

2.167

0.877–5.350

0.094

   

 BMI [kg/m2]

0.918

0.806–1.046

0.200

   

 Hypertension [%]

0.942

0.416–2.132

0.886

   

 Diabetes [%]

3.453

1.219–9.785

0.020*

4.937

1.497–16.278

0.009**

 Smoking [%]

1.541

0.565–4.199

0.398

   

 Drinking [%]

0.596

0.225–1.582

0.299

   

 LDL < 1.8mmol/L

1.551

0.659–3.653

0.315

   

 MLA [mm2]

0.512

0.185–1.415

0.197

   

 PB[%]

1.003

0.990–1.016

0.702

   

 MLD [mm]

0.635

0.237–1.704

0.368

   

 %DS [%]

1.005

0.969–1.041

0.804

   

 QFR

0.355

0.057–2.219

0.268

   

Procedure

 LAD [%]

2.143

1.008–4.555

0.048*

2.351

0.888–6.223

0.085

 LCX [%]

0.470

0.204–1.080

0.075

   

 RCA [%]

0.801

0.304–2.110

0.654

   

 Calcification lesion [%]

2.035

0.636–6.510

0.231

   

 IVUS use [%]

1.029

0.485–2.182

0.941

   

 Modified balloon [%]

0.668

0.325–1.376

0.274

   

 DCB diameter > 3mm [%]

0.579

0.257–1.306

0.188

   

 DCB length > 20mm [%]

1.066

0.472–2.408

0.878

   

 Post-procedural MLD [mm]

0.761

0.346–1.675

0.498

   

 Post-procedural QDR

1.601

0.001–2948

0.902

   

1-year follow-up

 LDL-C > 1.8mmol/L

2.550

1.178–5.519

0.017*

2.575

1.021–6.493

0.045*

 HbA1 > 6.5%

0.859

0.375–1.968

0.720

   
  1. OR, odds ratio; 95% CI, 95% confidence interval; BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; IVUS, intravascular ultrasound; MLA, minimum lumen area; PB, plaque burden; MLD, minimum lumen diameter; %DS, percentage diameter stenosis; QFR: quantitative flow ratio; DCB, drug-coated balloon; HbA1c, hemoglobin A1c.
  2. *P < 0.05, **P < 0.01.
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