Table 1 Relationship between GOLT1A expression and clinical characteristics in 499 PTC patients from the TCGA database.
From: High GOLT1A expression induces poor prognosis in papillary thyroid carcinoma
Characteristics | GOLT1A | t/χ2 | P-value | |
|---|---|---|---|---|
High expression | Low expression | |||
n = 250 | n = 249 | |||
Age | 36–58 | 34-58.5 | − 0.723 | 0.47 |
≥ 55 years, n (%) | 81 (32.5) | 84 (33.7) | 0.083 | 0.775 |
< 55 years, n (%) | 168 (67.5) | 165 (66.3) | ||
ETE | 6.56 | 0.01 | ||
Yes, n (%) | 90 (37.0) | 62 (26.2) | ||
No, n (%) | 153 (63.0) | 175 (73.8) | ||
Sex | 0.041 | 0.84 | ||
Male, n (%) | 68 (27.3) | 66 (26.5) | ||
Female, n (%) | 181 (72.7) | 183 (73.5) | ||
LNM | 4,744 | 0.029 | ||
Yes, n (%) | 125 (54.6) | 97 (44.3) | ||
No, n (%) | 104 (45.4) | 122 (55.7) | ||
Histological type | 14.755 | 0.001 | ||
Classical/usual, n (%) | 182 (74.6) | 172 (70.2) | ||
Follicular, n (%) | 36 (14.8) | 63 (25.7) | ||
Tall cell, n (%) | 26 (10.7) | 10 (4.1) | ||
Histological risk | 6.657 | 0.01 | ||
High, n (%) | 29 (11.6) | 13 (5.2) | ||
Low, n (%) | 220 (88.4) | 236 (94.8) | ||
T Stage | 1.533 | 0.216 | ||
T1-T2, n (%) | 146 (59.1) | 160 (64.5) | ||
T3-T4, n (%) | 101 (40.9) | 88 (35.5) | ||
Pathologic stage | 1.933 | 0.586 | ||
I, n (%) | 192 (77.7) | 195 (78.6) | ||
II, n (%) | 43 (17.4) | 45 (18.1) | ||
III, n (%) | 10 (4.0) | 5 (2.0) | ||
IV, n (%) | 2 (0.8) | 3 (1.2) | ||
Clinical stage | 1.264 | 0.261 | ||
I–II, n (%) | 234 (94.7) | 240 (96.8) | ||
III–IV, n (%) | 13 (5.3) | 8 (3.2) | ||
Focus | 0.518 | 0.472 | ||
Multifocal, n (%) | 116 (47.7) | 109 (44.5) | ||
Unifocal, n (%) | 127 (52.3) | 136 (55.5) | ||
Hashimoto’s thyroiditis | 0.914 | 0.339 | ||
Yes, n (%) | 29 (12.6) | 36 (15.7) | ||
No, n (%) | 201 (87.4) | 193 (84.3) | ||
BRAF Mutation | 16.597 | < 0.001 | ||
Yes, n (%) | 105 (42.5) | 148 (60.9) | ||
No, n (%) | 142 (57.5) | 95 (39.1) | ||
Subtype | 34.178 | < 0.001 | ||
BRAF-like, n (%) | 158 (83.6) | 112 (56.3) | ||
RAS-like, n (%) | 31 (16.4) | 87 (43.7) | ||
Differentiation risk | 28.925 | < 0.001 | ||
Yes, n (%) | 120 (63.5) | 72 (36.2) | ||
No, n (%) | 69 (36.5) | 127 (63.8) | ||
TDS | − 1.0515 ± 0.168 | − 0.561 ± 1.49 | − 6.72 | < 0.001 |
