Table 1 Baseline characteristics of the study participants.

From: Risk of pancreatic cancer according to glycemic status in nonalcoholic fatty liver disease: a nationwide cohort study

 

Pancreatic cancer

 

No

(n = 1089708)

Yes

(n = 4124)

P value

Age (years), mean ± SD

49.1 ± 13.4

61.7 ± 10.8

< 0.001

Age groups, years, n (%)

20–40

290,545 (26.7)

131 (3.2)

< 0.001

40–64

637,037 (58.5)

2192 (53.2)

≥ 65

162,126 (14.9)

1801 (43.7)

Sex, n (%)

  

< 0.001

Men

798,218 (73.3)

2695 (65.4)

Women

291,490 (26.7)

1429 (34.6)

Smoking, n (%)

  

< 0.001

Never

517,424 (47.5)

2204 (53.4)

Former

203,519 (18.7)

791 (19.2)

Current

368,765 (33.8)

1129 (27.4)

Alcohol consumption, n (%)

  

< 0.001

None

503,467 (46.2)

2373 (57.5)

Light-to-moderate

586,241 (53.8)

1751 (42.5)

Regular exercise, n (%)

197,388 (18.1)

825 (20.0)

0.002

Low income (< 25%), n (%)

211,197 (19.4)

914 (22.2)

< 0.001

Anthropometrics, mean ± SD

BMI (kg/m2)

26.4 ± 2.8

26.2 ± 2.8

< 0.001

Waist circumference (cm)

88.0 ± 6.6

89.1 ± 6.8

< 0.001

Systolic BP (mm Hg)

127.6 ± 14.6

130.7 ± 15.7

< 0.001

Diastolic BP (mm Hg)

79.7 ± 9.8

80.2 ± 10.1

< 0.001

Laboratory findings, mean ± SD

Fasting glucose (mg/dL)

102.8 ± 28.5

109.6 ± 34.0

< 0.001

Total cholesterol (mg/dL)

206.9 ± 38.0

203.8 ± 40.0

< 0.001

HDL cholesterol (mg/dL)

51.2 ± 30.6

51.9 ± 34.4

0.206

LDL cholesterol (mg/dL)

118.0 ± 42.3

115.6 ± 40.1

< 0.001

Triglycerides (mg/dL)

176.2 (176.0–176.4)

170.3 (167.8–172.8)

< 0.001

eGFR (mL/min/1.73 m2)

85.4 ± 46.8

81.8 ± 41.4

< 0.001

Comorbidities, n (%)

Diabetes mellitus

153,172 (14.1)

1094 (26.5)

< 0.001

Hypertension

411,436 (37.8)

2366 (57.4)

< 0.001

Dyslipidemia

305,485 (28.0)

1386 (33.6)

< 0.001

CKD

89,572 (8.2)

597 (14.5)

< 0.001

Pancreatitis

748 (0.07)

8 (0.19)

0.002

Cholangitis

208 (0.02)

3 (0.07)

0.007

  1. IFG, impaired fasting glucose; SD, standard deviation; BMI, body mass index; BP, blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; eGFR, estimated glomerular filtration rate; CKD, chronic kidney disease.
  2. SI conversion factors: To convert total cholesterol to mmol/L, multiply by 0.0259; HDL cholesterol to mmol/l, multiply by 0.0259; LDL cholesterol to mmol/L, multiply by 0.0259; triglycerides to mmol/L, multiply by 0.0113.