Fig. 8 | Scientific Reports

Fig. 8

From: Unlocking the potential of phytochemicals in inhibiting SARS-CoV-2 MPro protein - an in silico and cell-based approach

Fig. 8

Antiviral activity and cytotoxicity of phytochemicals against SARS-CoV-2. (A) Dose-response curve for Remdesivir (control), showing viral inhibition (blue) and cell viability (red), EC50 = 3 µM. (B) Evaluation of Shikonin (EC50 = 10 µM), Demethoxycurcumin (EC50 = 8.8 µM), and Withaferin A (EC50 = 2.8 µM). FA denotes the fraction of cells affected; GRI represents the predicted compound response at an infinite concentration.

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