Table 2 Solution stability of linezolid drug in phosphate buffer in different pH 6.8, 7.0 and 7.4.
From: Calcium alginate medicated dressing for enhanced absorption in diabetic foot ulcer management
Assay analysis result | |||||||
|---|---|---|---|---|---|---|---|
Standard name | Sample weight | Dilution | Aliquot | Dilution | PPM | Potency | LC |
Linezolid | 50.21 | 50 | 2.5 | 50 | 50.21 | 99.79 | 1 |
1 | 2 | 3 | Mean | SD | %RSD | ||
|---|---|---|---|---|---|---|---|
Std area | 2,611,635 | 2,611,635 |
Sample name | Sample weight | Dilution | Aliquot | Dilution | Area | % Assay | |
|---|---|---|---|---|---|---|---|
6.8 Phosphate buffer | 99.9 | 100 | 1 | 20 | 2,784,610 | 106.95 | |
7.0 Phosphate Buffer | 100.5 | 100 | 1 | 20 | 2,781,352 | 106.19 | |
7.4 Phosphate Buffer | 100.2 | 100 | 1 | 20 | 2,720,329 | 104.17 |
