Fig. 6

Analysis of Genetic Alterations. (A) The heatmap illustrates the correlation between PPIA mRNA expression and mRNA expression of RNA modification genes (including m1A, m5C, m6A). Spearman correlation analysis was used for statistical evaluation. (B) The heatmap shows the correlation between PPIA mRNA expression and DNA methylation sites. Spearman correlation analysis was employed for statistical evaluation. Symbols *, **, and *** denote P < 0.05, P < 0.01, and P < 0.001, respectively.