Table 2 Characteristics of preterm infants with and without iNO administration.
Variable | iNO (n = 20) | N-iNO (n = 36) | P-value |
|---|---|---|---|
Age, (mean ± SD weeks) | 29.3 ± 2.4 | 28.2 ± 1.9 | 0.06 |
Gender (male/female) | 12/8 | 18/18 | 0.47 |
Weight, (mean ± SD g) | 1246 ± 402 | 1071 ± 259 | 0.12 |
Apgar 1 min, (median, quartile) | 6 (4,8) | 6 (4,9) | 0.24 |
Apgar 5 min, (median, quartile) | 8.5 (7,9) | 8.5 (8,9) | 0.39 |
Before treatment P/F ratio, n (%) (%) | 139.0 ± 76.3 | 124.9 ± 49.1 | 0.61 |
24 h After treatment P/F ratio, n (%) | 262.0 ± 92.8 | 276.7 ± 94.9 | 0.60 |
Cesarean, n (%) | 12 (60.0) | 23 (63.9) | 0.77 |
Twin, n (%) | 5 (25.0) | 13 (36.1) | 0.16 |
SGA, n (%) | 1 (5.0) | 5 (13.9) | 0.56 |
PROM, n (%) | 5 (25.0) | 6 (16.7) | 0.69 |
GDM, n (%) | 0 | 0 | – |
Abortion history, n (%) | 8 (40.0) | 14 (63.6) | 0.94 |
PIH, n (%) | 3 (15.0) | 5 (13.9) | 0.976 |
RDS, n (%) | 14 (70.0) | 17 (47.2) | 0.10 |
EOS, n (%) | 16 (80.0) | 14 (38.9) | 0.003 |
PDA, n (%) | 11 (55.0) | 15 (41.7) | 0.34 |
Pneumothorax, n (%) | 2 (10.0) | 3 (8.3) | 0.78 |
MAS, n (%) | 1 (5.0) | 2 (5.6) | 0.59 |
Surfactant, n (%) | 14 (70.0) | 16 (44.4) | 0.07 |
Mechanical ventilation, n (%) | 19 (95.0) | 29 (80.6) | 0.14 |
Sildenafil, n (%) | 10 (50.0) | 19 (52.8) | 0.84 |
Milrinone, n (%) | 12 (60.0) | 10 (27.8) | 0.02 |
Vasoconstrictive drug, n (%) | 8 (40.0) | 17 (47.2) | 0.60 |
BPD, n (%) | 3 (15.0) | 23 (63.9) | 0.01 |
ROP, n (%) | 1 (5.0) | 10 (27.8) | 0.08 |
IVH, n (%) | 5 (25.0) | 8 (22.2) | 0.92 |
NEC, n (%) | 1 (5.0) | 3 (8.3) | 0.94 |
Death, n (%) | 0 | 0 | – |
