Table 1 Weighted characteristics of participants with and without NAFLD status.

From: Utility of the serum alanine aminotransferase to high density lipoprotein cholesterol ratio in evaluating nonalcoholic fatty liver disease and liver fibrosis

Characteristics

Non-NAFLD

(n = 3251)

NAFLD

(n = 1513)

P value

Age (years)

40.70 ± 19.83

49.11 ± 17.21

< 0.0001

Age (%)

  

< 0.0001

< 20

17.49

4.78

 

≥ 20, < 40

35.30

25.97

 

≥ 40, < 60

26.20

39.13

 

≥ 60

21.01

30.12

 

Gender (%)

  

< 0.0001

Male

42.25

53.67

 

Female

57.75

46.33

 

Race (%)

  

< 0.0001

Mexican American

8.56

13.91

 

Other Hispanic

7.53

6.03

 

Non-Hispanic White

60.43

61.63

 

Non-Hispanic Black

12.07

8.28

 

Non-Hispanic Asian

6.39

5.69

 

Other Race

5.02

4.47

 

Smoking behavior (%)

  

< 0.0001

Never smoke

71.24

60.56

 

Ever smoke

17.73

26.38

 

Current smoke

11.03

13.06

 

Hypertension (%)

  

< 0.0001

No

72.11

43.39

 

Yes

27.90

56.61

 

T2DM

  

< 0.0001

No

93.33

74.03

 

Yes

6.68

25.97

 

Physical activity level

  

0.1159

inactive

49.46

46.89

 

moderate

8.53

10.17

 

active

42.01

42.95

 

BMI (Kg/m2)

26.60 ± 6.04

34.30 ± 7.36

< 0.0001

BMI (%)

  

< 0.0001

< 25

43.74

5.12

 

≥ 25, < 30

32.13

25.39

 

≥ 30

24.14

69.49

 

WC (cm)

91.35 ± 15.19

112.12 ± 15.53

< 0.0001

HC (cm)

102.05 ± 12.28

115.56 ± 14.82

< 0.0001

SBP(mmHg)

118.47 ± 17.46

127.08 ± 16.92

< 0.0001

DBP(mmHg)

69.82 ± 12.07

74.19 ± 12.17

< 0.0001

PLT (109/L)

245.31 ± 59.68

253.33 ± 62.01

< 0.0001

CRP (mg/L)

2.87 ± 6.52

4.96 ± 7.77

< 0.0001

Fast glucose (mmol/L)

5.70 ± 1.08

6.66 ± 2.19

< 0.0001

Fast insulin (mIU/L)

9.83 ± 9.05

18.86 ± 15.15

< 0.0001

Glycohemoglobin (%)

5.44 ± 0.63

5.99 ± 1.10

< 0.0001

ALT (IU/L)

18.76 ± 13.41

27.88 ± 19.54

< 0.0001

GGT (IU/L)

21.64 ± 24.61

34.82 ± 37.31

< 0.0001

AST (IU/L)

20.54 ± 10.34

23.07 ± 13.13

< 0.0001

ALP (IU/L)

86.83 ± 55.23

82.52 ± 31.55

0.0048

TBIL (mg/dL)

0.48 ± 0.30

0.44 ± 0.25

< 0.0001

TG (mg/dL)

113.33 ± 70.13

179.65 ± 122.69

< 0.0001

TC (mg/dL)

181.56 ± 39.28

189.99 ± 40.45

< 0.0001

HDL-C (mg/dL)

56.38 ± 14.56

47.75 ± 13.08

< 0.0001

LDL-C (mg/dL)

105.20 ± 33.67

113.17 ± 36.45

< 0.0001

SUA (mg/dL)

5.06 ± 1.32

5.80 ± 1.42

< 0.0001

ALT/HDL-C

0.37 ± 0.31

0.64 ± 0.51

< 0.0001

CAP (dB/m)

222.92 ± 40.32

331.69 ± 32.79

< 0.0001

LSM (kPa)

4.91 ± 2.90

7.28 ± 7.03

< 0.0001

  1. Mean ± SD was for continuous variables. The weighted linear regression model calculated the p-value. % was for categorical variables. The weighted chi-square test calculated the p-value. Abbreviations: NAFLD, Non-alcoholic fatty liver disease; T2DM, Type 2 diabetes; BMI, Body mass index; SBP, Systolic blood pressure; DBP, Diastolic blood pressure; PLT, Platelet; CRP, C-Reactive Protein; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase; GGT, Gamma-glutamyl transpeptidase; AKP, Alkaline phosphatase; TBIL, Total bilirubin; HbA1c, Glycosylated hemoglobin A1c; TG, Triglycerides; TC, Total cholesterol; HDL-C, High-density lipoprotein cholesterol; LDL-C, Low-density lipoprotein cholesterol; SUA, Serum uric acid; LSM, Liver stiffness measurement; CAP, Controlled attenuation parameter.
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