Table 1 Basic characteristics of participants.

From: Systemic inflammation partially mediates the association between lipid accumulation and osteoarthritis in normal BMI adults

Characteristic

N

Overall

N = 2408

LAP (group)

P Value

T1

N = 803

T2

N = 802

T3

N = 803

Age (years)

2408

43.85 ± 17.68

40.71 ± 16.79

44.68 ± 18.33

46.49 ± 17.39

 < 0.001

Sex(group)

2408

    

 < 0.001

 Female

 

1,240 (55%)

803 (100%)

409 (54%)

28 (4.2%)

 

 Male

 

1,168 (45%)

0 (0%)

393 (46%)

775 (96%)

 

Race(group)

2408

    

 < 0.001

 Non-hispanic White

 

1,031 (69%)

332 (67%)

347 (71%)

352 (70%)

 

 Other/multiracial

 

567 (12%)

222 (15%)

149 (9.6%)

196 (13%)

 

 Non-hispanic black

 

372 (7.7%)

98 (6.3%)

163 (10.0%)

111 (6.5%)

 

 Mexican American

 

223 (5.5%)

65 (4.8%)

78 (5.6%)

80 (6.1%)

 

 Other hispanic

 

215 (5.4%)

86 (6.9%)

65 (4.1%)

64 (5.1%)

 

Education(group)

2408

    

 < 0.001

 Above high school

 

1,502 (69%)

584 (79%)

475 (67%)

443 (61%)

 

 Below high school

 

428 (12%)

91 (6.9%)

143 (11%)

194 (17%)

 

 High school

 

478 (19%)

128 (14%)

184 (22%)

166 (22%)

 

Smoke(group)

2408

    

 < 0.001

 Current smoker

 

516 (21%)

99 (12%)

194 (22%)

223 (28%)

 

 Former smoker

 

442 (20%)

107 (15%)

142 (21%)

193 (23%)

 

 Never smoker

 

1,450 (60%)

597 (72%)

466 (57%)

387 (49%)

 

Drink(group)

2408

    

 < 0.001

  < 12 drinks/year

 

2,233 (94%)

773 (97%)

758 (96%)

702 (89%)

 

  ≥ 12 drinks/year

 

175 (5.9%)

30 (3.4%)

44 (4.2%)

101 (11%)

 

 BMI-z

2408

2.30 ± 0.24

2.18 ± 0.23

2.33 ± 0.24

2.41 ± 0.19

 < 0.001

 WHtR-z

2408

2.39 ± 0.44

2.21 ± 0.31

2.45 ± 0.50

2.51 ± 0.41

 < 0.001

Hypertension(group)

2408

    

 < 0.001

 Hypertension

 

462 (16%)

116 (11%)

161 (18%)

185 (21%)

 

 Non-hypertension

 

1,946 (84%)

687 (89%)

641 (82%)

618 (79%)

 

DM(group)

2408

    

 < 0.001

 DM

 

128 (3.3%)

15 (0.9%)

41 (3.0%)

72 (6.3%)

 

 Non-DM

 

2,280 (97%)

788 (99%)

761 (97%)

731 (94%)

 

 SIRI

2408

1.08 ± 0.82

0.95 ± 0.64

1.03 ± 0.85

1.27 ± 0.92

 < 0.001

 log2(SIRI)

2408

0.68 ± 0.30

0.63 ± 0.26

0.65 ± 0.31

0.76 ± 0.32

 < 0.001

OA(group)

2408

    

 < 0.001

 Non-osteoarthritis

 

2,198 (90%)

751 (93%)

732 (91%)

715 (89%)

 

 Osteoarthritis

 

210 (10%)

52 (6.5%)

70 (8.7%)

88 (11%)

 
  1. BMI-z, WHtR-z, and LAP-z are standardized scores calculated based on the 2005–2012 NHANES weighted overall mean and standard deviation. Standardized weighted means and SDs may not be strictly 0 and 1 due to the complex weighted sampling design.
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