Fig. 4

Differential expression and functional enrichment analysis in KRAS-mutant CRC with high vs. low SLC16A3 expression. (A) Volcano plot of differentially expressed genes (DEGs) between high and low SLC16A3 expression groups (|log2FC| > 1, p < 0.05). (B) Circular plot showing GO enrichment of DEGs across biological process, cellular component, and molecular function categories. (C) Bar plot of top GO terms enriched in DEGs. (D) KEGG pathway enrichment bubble plot showing significantly enriched pathways. Dot size indicates gene count; color represents p-value.