Table 3 Values of echocardiographic indices in the diagnosis of HFpEF.

From: Left atrioventricular coupling index measured by echocardiography in heart failure with preserved ejection fraction

Parameters

AUC

95% CI

p value

Cutoff point

Sensitivity

Specificity

P vs. LACI*

LACI (%)

0.951

0.921 to 0.981

< 0.001

33.07

97.1%

87.3%

-

LV GLS (%)

0.586

0.482 to 0.689

0.130

18.55

61.8%

61.1%

< 0.001

LASr (%)

0.694

0.583 to 0.804

0.002

22.69

60.0%

77.4%

< 0.001

LAScd (%)

0.685

0.580 to 0.790

0.004

13.62

84.0%

54.8%

< 0.001

LASct (%)

0.584

0.463 to 0.705

0.190

16.00

76.0%

50.0%

< 0.001

LAVI (ml/m²)

0.662

0.548 to 0.776

0.004

34.00

41.2%

91.3%

< 0.001

E/e’ ratio

0.505

0.324 to 0.685

0.960

14.00

9.1%

91.8%

< 0.001

TRV (cm/s)

0.589

0.409 to 0.769

0.290

280.00

23.1%

94.7%

< 0.001

e’ septal (cm/s)

0.618

0.452 to 0.785

0.200

7.00

72.7%

50.9%

< 0.001

e’ lateral (cm/s)

0.564

0.395 to 0.732

0.490

10.00

81.8%

30.9%

< 0.001

  1. *P-value from DeLong test comparing AUC of each variable with that of LACI. LAVI, left atrial volume index; e’ lateral, lateral early diastolic mitral annular velocity; e’ septal, septal early diastolic mitral annular velocity; E/e’ ratio, average ratio of early diastolic mitral inflow velocity to early diastolic mitral annular velocity; TRV, maximum tricuspid regurgitant velocity; LV GLS, left ventricular global longitudinal strain; LASr, left atrial reservoir strain; LAScd, left atrial conduit strain; LASct, left atrial contractile strain; LACI, left atrioventricular coupling index.
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