Fig. 2
Oxtr co-expression with dopamine receptor cell classes is greater in prairie voles compared to meadow voles in the nucleus accumbens. (A–C) Quantification of cell proportions based on transcript combinations the nucleus accumbens core (A), medial shell (B), and lateral shell (C) in meadow voles and prairie voles (light green and darker green respectively in radar plot). Fold change of prairie:meadow vole of each transcript combination was quantified and compared between species for each subregion. Meadow voles had a significantly greater number of Drd2 only and Drd1 + Drd2 cells compared to prairie voles in all subregions. Prairie voles demonstrated significantly higher levels of Oxtr co-expressing transcripts as compared to meadow voles in the lateral shell. Co-expression of Oxtr does not appear to be biased towards a particular Drd receptor class as co-expression is found with Drd1, Drd2, and Drd1 + Drd2 cells in all subregions. Error bars show EP (error propagation). N = 12–13 per group. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
