Fig. 8 | Scientific Reports

Fig. 8

From: Enhancing the selectivity and conditional sensitivity of an antimicrobial peptide through cleavage simulations and homoarginine incorporation to combat drug-resistant bacteria

Fig. 8

In vivo toxicity and antibacterial potentials of peptide 7 in infected larvae models. For toxicity, larvae worms were treated with 4 × MIC of peptide 7. For in vivo antibacterial tests, larvae infected with E. coli strains ATCC 2340, NCTC 13,846, and ATCC 2469 were treated with varying doses of peptide 7. Colistin (10 × MIC) was set as control group. The untreated group refers to larvae that received no peptide or antibiotics treatment and were treated solely with the vehicle, PBS.

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