Fig. 7 | Scientific Reports

Fig. 7

From: Acteoside ameliorates cerebral ischemia/reperfusion injury in MCAO rats as a natural plasma Kallikrein inhibitor from Osmanthus fragrans flower

Fig. 7

Acteoside inhibited inflammation by NF-κB pathway in MCAO rats. MCAO rats were treated with acteoside once and collected blood or brain samples 24 h post-reperfusion, n = 10 in each group. (A) Representative western blot image of IκB, p65, and p-p65 in infract brain tissue. (B-C) The concentration of inflammatory factors in serum. B) TNF-α, C) IL-1β. The values were expressed as Means ± SEM. ***P < 0.001 vs. Ctrl group, #P < 0.05, ##P < 0.01, ###P < 0.001 vs. model group. Abbreviations: IκB, inhibitor of NF-κB; TNF-α, Tumor necrosis factor; IL-1β, Interleukin-1 beta.

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