Table 3 Comparison of macular, ganglion cell layer and peripapillary retinal nerve fiber layer thickness in patient and control groups.

From: Lamina cribrosa curvature depth and index as novel parameters in Graves’ ophthalmopathy

 

GO Group

(n = 70)

Control Group

(n = 70)

p

Macular thickness parameters (µm)

 Central foveal thickness

265.7 ± 20.1

265.8 ± 21.4

0.958a

 Superior pericentral thickness

340(331–352)

343(333–354)

0.439b

 Inferior pericentral thickness

335.5(328–348)

341.5(327–352)

0.143b

 Nasal pericentral thickness

336.5(328-352.25)

343.5(331–355)

0.143b

 Temporal pericentral thickness

324(317.75–336)

332(318–340)

0.077b

 Superior peripheral thickness

299(289–305)

297(288–307)

0.902b

 Inferior peripheral thickness

288.4 ± 12.5

287 ± 15.3

0.532a

 Nasal peripheral thickness

316.2 ± 14.6

317.4 ± 15.5

0.647a

 Temporal peripheral thickness

280.5 ± 12.8

280.2 ± 14.6

0.908a

GCLT parameters (µm)

 Central foveal GCLT

13(11–15)

13(11–15)

0.536b

 Superior pericentral GCLT

53(51–55)

53(51–57)

0.467b

 Inferior pericentral GCLT

53 ± 3.7

53.4 ± 5.6

0.613a

 Nasal pericentral GCLT

51(47–53)

50.5(48–55)

0.465b

 Temporal pericentral GCLT

48(45–51)

48(46–53)

0.691b

 Superior peripheral GCLT

35.5(33–38)

36(33–38)

0.651b

 Inferior peripheral GCLT

34(32–35)

34(31–47)

0.983b

 Nasal peripheral GCLT

40(38–42)

40(37–42)

0.900b

 Temporal peripheral GCLT

35.8 ± 3.2

35.9 ± 4.8

0.887a

RNFLT parameters (µm)

 RNFLT, global

102.8 ± 8.5

100.7 ± 11.8

0.226a

 RNFLT, superior-nasal

109.9 ± 19.2

113.4 ± 23.4

0.336a

 RNFLT, temporal-nasal

141.5 ± 17.6

140.1 ± 19.4

0.663a

 RNFLT, inferior-nasal

121.5 ± 24.1

114.2 ± 23.1

0.060a

 RNFLT, inferior-temporal

147.5 (135.7–162.5)

139 (131.0–153.0)

0.052b

 RNFLT, nasal

77.9 ± 14.7

75.2 ± 14.6

0.290a

 RNFLT, temporal

73.2 ± 10.3

72.9 ± 11.5

0.842a

  1. GO: Graves’ Ophthalmopathy, GCLT: ganglion cell layer thickness, RNFLT: retinal nerve fiber layer thickness.
  2. aIndependent samples t-test, bMann Whitney U test.