Fig. 2 | Scientific Reports

Fig. 2

From: Association of DNA damage response pathway genes with rheumatoid arthritis risks: a case-control study

Fig. 2

Expression analysis of ATM gene in RA patients. (A) Significant downregulation of ATM gene was observed in RA patients compared to controls. (B) Non-significant association of ATM gene with different gender (males vs. females) and age group (< 45years vs. > 45years) of RA patients. (C) Significant deregulation of the ATM gene was observed in different clinicopathological parameters of RA patients such as Anti-CCP, ESR, and CRP. (D) Significant downregulation of ATM gene was observed in RA patients using the methotrexate compared to patients using biologics. Level of significance p < 0.05.

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