Table 4 Haplotype analysis of DNA damage pathway gene SNPs in RA patients and controls.

From: Association of DNA damage response pathway genes with rheumatoid arthritis risks: a case-control study

SNP1

SNP2

SNP3

SNP4

Cases

Controls

X2

OR 95%CI

p-value

C

C

C

A

22.87 (0.023)

13.84 (0.014)

-

-

-

C

C

T

G*

21.13 (0.021)

105.16 (0.105)

56.3

0.191 (0.118 ~ 0.307)

7.34e-014

C

G

C

A

25.13 (0.025)

0.16

-

-

-

C

G

C

G

0

4.00 (0.004)

-

-

-

C

G

T

G*

468.87 (0.469)

136.84 (0.137)

289.65

6.262 (5.012 ~ 7.824)

0.00e + 000

T

C

C

A*

426 (O.426)

712 (0.713)

155.191

0.295 (0.243 ~ 0.359)

8.88e-016

T

C

C

G

0

26 (0.026)

-

-

-

C

G

T

A

12 (0.012)

0

-

-

-

T

C

T

A

24 (0.024)

0

-

-

-

  1. SNP1 = Val762Ala, SNP2 = Pro1054Arg, SNP3 = Ala138Val, SNP4 = Tyr177Tyr.
  2. OR = odds ratio, 95% CI = 95% confidence interval, p < 0.05.
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