Table 3 Pharmacokinetic parameters of Recombinant insulin lisargine solution and Lantus (insulin glargine).

From: X-ray crystallography reveals insulin lisargine structure and mechanisms of glucose regulation

Dosing Group

Dose (IU/kg)

AUC 0-t (mU·h/mL)

Cmax (mU/mL)

Tmax (h)

Recombinant Insulin Lisargine Solution

0.5

3.48 ± 1.21

2.15 ± 0.93

1.10 ± 0.32

1

13.88 ± 2.49

7.73 ± 2.15

1.00 ± 0.00

1.5

83.66 ± 17.10

26.34 ± 7.55

1.56 ± 0.53

Lantus (Control)

1.5

62.94 ± 13.83

15.95 ± 8.19

1.90 ± 0.88

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