Fig. 1

Boxplot of spirochete counts by biopsy location and morphology. Box limits are interquartile range, and center line is median. Whiskers represent 1.5x IQR. Homogeneous EM lesions contain a higher number of spirochetes in the central zone compared to annular EM lesions (Two-sided Wilcoxon rank sum test: p = 0.014, 95% CI 12.7 to 6134). Dots colorized red if there was a visible tick bite reaction within the EM.