Table 1 General characteristics of study subjects according to PRSMetS.
Variables | Total (n = 4987) | Low PRSMetS (n = 4671) | High PRSMetS (n = 316) | p-value |
|---|---|---|---|---|
Clinical characteristics | ||||
Age (years) | 55.53 ± 8.28 | 55.57 ± 8.32 | 54.93 ± 7.64 | 0.150 |
Men | 3632 (72.8) | 3388 (72.5) | 244 (77.2) | 0.070 |
Height (cm) | 167.56 ± 7.75 | 167.50 ± 7.75 | 168.10 ± 7.73 | 0.202 |
Weight (kg) | 67.96 ± 11.00 | 67.91 ± 11.01 | 68.74 ± 10.86 | 0.198 |
BMI (kg/m²) | 24.10 ± 2.79 | 24.09 ± 2.79 | 24.22 ± 2.78 | 0.410 |
Waist circumference (cm) | 85.94 ± 7.73 | 85.93 ± 7.75 | 86.04 ± 7.43 | 0.812 |
Diabetes mellitus | 686 (13.8) | 639 (13.7) | 47 (14.9) | 0.551 |
Antidiabetic medication | 268 (5.4) | 249 (5.3) | 19 (6.0) | 0.603 |
Hypertension | 1735 (34.8) | 1613 (34.5) | 122 (38.6) | 0.141 |
Antihypertensive medication | 1071 (21.5) | 987 (21.1) | 84 (26.6) | 0.022 |
Hyperlipidaemia | 1477 (29.6) | 1342 (28.7) | 135 (42.7) | < 0.0001 |
Statin | 742 (14.9) | 677 (14.5) | 65 (20.6) | 0.003 |
Chronic kidney disease | 101 (2.0) | 98 (2.1) | 3 (1.0) | 0.161 |
Systolic blood pressure (mmHg) | 118.72 ± 13.22 | 118.70 ± 13.30 | 119.00 ± 12.08 | 0.680 |
Diastolic blood pressure (mmHg) | 78.75 ± 9.97 | 78.73 ± 10.02 | 79.04 ± 9.33 | 0.594 |
Fasting glucose (mg/dL) | 103.74 ± 20.52 | 103.70 ± 20.63 | 104.00 ± 18.79 | 0.767 |
Triglycerides (mg/dL) | 125.97 ± 76.56 | 125.10 ± 76.03 | 138.40 ± 83.20 | 0.006 |
Total cholesterol (mg/dL) | 195.76 ± 37.62 | 195.20 ± 37.24 | 203.40 ± 42.12 | 0.001 |
HDL-C (mg/dL) | 51.60 ± 12.12 | 51.61 ± 12.10 | 51.43 ± 12.49 | 0.797 |
LDL-C (mg/dL) | 124.71 ± 32.49 | 124.40 ± 32.14 | 129.80 ± 36.86 | 0.010 |
eGFR (mL/min/1.73 m2) | 88.03 ± 14.65 | 88.01 ± 14.71 | 88.29 ± 13.77 | 0.743 |
HbA1c (%) | 5.82 ± 0.67 | 5.82 ± 0.68 | 5.80 ± 0.60 | 0.554 |
hs-CRP (mg/L) | 0.13 ± 0.39 | 0.13 ± 0.34 | 0.15 ± 0.85 | 0.615 |
Lifestyle risk component | ||||
Obesity | 0.198 | |||
Obese (BMI ≥ 25 kg/m2) | 1755 (35.2) | 1644 (35.2) | 111 (35.1) | |
Overweight (23 ≤ BMI < 25 kg/m2) | 1538 (30.8) | 1428 (30.6) | 110 (34.8) | |
Normal (BMI < 23 kg/m2) | 1694 (34.0) | 1599 (34.2) | 95 (30.1) | |
Physical activity | 0.715 | |||
Inactive | 2920 (58.6) | 2737 (58.6) | 183 (57.9) | |
Minimally active | 1699 (34.1) | 1593 (34.1) | 106 (33.5) | |
Health-enhancing physical activity | 368 (7.4) | 341 (7.3) | 27 (8.5) | |
Smoking | 0.329 | |||
Current smoker | 953 (19.1) | 901 (19.3) | 52 (16.5) | |
Ex-smoker | 2611 (52.4) | 2434 (52.1) | 177 (56.0) | |
Non-smoker | 1423 (28.5) | 1336 (28.6) | 87 (27.5) | |
Diet | 0.561 | |||
Poor diet | 831 (16.7) | 785 (16.8) | 46 (14.6) | |
Intermediate diet | 3321 (66.6) | 3107 (66.5) | 214 (67.7) | |
Ideal diet | 835 (16.7) | 779 (16.7) | 56 (17.7) | |
Alcohol consumption | 0.420 | |||
> 14 drinks per week | 1370 (27.5) | 1277 (27.3) | 93 (29.4) | |
Healthy lifestyle score (points) | 4.30 ± 1.69 | 4.30 ± 1.69 | 4.30 ± 1.58 | 0.936 |
Healthy lifestyle score | 0.051 | |||
0 | 25 (0.5) | 22 (0.5) | 3 (1.0) | |
1 | 184 (3.7) | 179 (3.8) | 5 (1.6) | |
2 | 526 (10.6) | 503 (10.8) | 23 (7.3) | |
3 | 934 (18.7) | 860 (18.4) | 74 (23.4) | |
4 | 1052 (21.1) | 974 (20.9) | 78 (24.7) | |
5 | 1072 (21.5) | 1013 (21.7) | 59 (18.7) | |
6 | 704 (14.1) | 657 (14.1) | 47 (14.9) | |
7 | 347 (7.0) | 328 (7.0) | 19 (6.0) | |
8 | 120 (2.4) | 113 (2.4) | 7 (2.2) | |
9 | 23 (0.5) | 22 (0.5) | 1 (0.3) | |
Lifestyle status | 0.027 | |||
Poor lifestyle | 735 (14.7) | 704 (15.1) | 31 (9.8) | |
Intermediate lifestyle | 3058 (61.3) | 2847 (61.0) | 211 (66.8) | |
Ideal lifestyle | 1194 (23.9) | 1120 (24.0) | 74 (23.4) | |
