Table 3 Univariate and multivariate Cox regression analysis for OS in NSCLC.
From: SREBP-2 promotes cancer progression through the mevalonate-Akt pathway in non-small cell lung cancer
Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Gender | ||||||
 Male | 1 |  |  |  |  |  |
 Female | 1.008 | 0.714–1.424 | 0.963 |  |  |  |
Age (year) | ||||||
 ≤ 60 | 1 |  |  |  |  |  |
 > 60 | 1.233 | 0.886–1.716 | 0.214 |  |  |  |
Stage | ||||||
 I-IIa | 1 |  |  | 1 |  |  |
 IIb-IV | 1.883 | 1.307–2.712 | 0.001 | 1.827 | 1.296–2.575 | 0.001 |
Tumor size (cm) | ||||||
 ≤ 3.0 | 1 |  |  |  |  |  |
 > 3.0 | 0.968 | 0.656–1.429 | 0.871 |  |  |  |
SREBP-2 | ||||||
 Low | 1 |  |  | 1 |  |  |
 High | 1.507 | 1.081–2.102 | 0.016 | 1.565 | 1.133–2.161 | 0.007 |
