Table 3 Dialysis efficiency and adequacy metrics, highlighting superior small and middle molecule clearance with HDF, while nutritional parameters remained comparable between groups.
Parameters | Total | HD | HDF | Test | p-value |
|---|---|---|---|---|---|
Patients (n) | 286 | 144 | 142 | ||
PR Urea (%) Median [Q1_Q3] | 77.2 [73.3 ; 81.1] | 75.9 [72.1 ; 80.3] | 78.5 [74.9 ; 81.3] | Wilcoxon test | 0.008 |
Kt/V‡ Median [Q1_Q3] | 1.7 [1.5 ; 1.9] | 1.7 [1.5 ; 1.9] | 1.8 [1.6 ; 2.0] | Wilcoxon test | 0.009 |
Kt (L/ses) ‡ Median [Q1_Q3] | 63.1 [55.2 ; 71.8] | 62.4 [52.0 ; 69.3] | 64.8 [57.1 ; 75.7] | Wilcoxon test | 0.013 |
nPCR (g/kg/24 h) Median [Q1_Q3] | 1.1 [1.0 ; 1.3] | 1.1 [1.0 ; 1.2] | 1.1 [0.9 ; 1.3] | Wilcoxon test | 0.946 |
ß2Mpre (mg/l) ‡ Median [Q1_Q3] | 26.2 [22.9 ; 30.5] | 26.9 [23.4 ; 30.9] | 26.0 [22.5 ; 29.9] | Wilcoxon test | 0.122 |
ß2Mpost.eq (mg/l) ‡ Median [Q1_Q3] | 9.3 [7.3 ; 11.9] | 10.9 [9.0 ; 13.9] | 8.1 [6.6 ; 10.2] | Wilcoxon test | < 0.001 |
PR ß2M (%) Median [Q1_Q3] | 63.2 [55.9 ; 71.1] | 58.7 [51.7 ; 63.8] | 69.6 [62.2 ; 73.0] | Wilcoxon test | < 0.001 |
ß2M TAC (mg/l) ‡ Median [Q1_Q3] | 16.3 [13.9 ; 19.1] | 17.3 [15.3 ; 20.5] | 15.1 [12.9 ; 17.9] | Wilcoxon test | < 0.001 |
Effective Kß2M (ml/min) Median [Q1_Q3] | 52.5 [41.9 ; 61.9] | 44.1 [38.0 ; 54.7] | 59.3 [50.2 ; 68.5] | Wilcoxon test | < 0.001 |
ß2M Mass removal (mg/ses) Median [Q1_Q3] | 197.5 [157.5 ; 240.9] | 183.2 [142.3 ; 219.3] | 209.5 [169.2 ; 253.6] | Wilcoxon test | 0.002 |
