Fig. 5

NCPD and CPDT of DMEM(LG), DMEM(HG) and the DMEM(LG)-PI3K inhibitor at passage 3. (a) The NCPD of the DMEM(LG) group was significantly greater than that of the DMEM(HG) and DMEM(LG)-PI3K inhibitor groups at passage 3. There was no significant difference between the DMEM(LG) group and the DMEM(LG)-DMSO group. (b) The CPDT of the DMEM(LG) group was significantly lower than that of the DMEM(HG) and DMEM(LG)-PI3K inhibitor groups at passage 3. There was no significant difference between the DMEM(LG) group and the DMEM(LG)-DMSO group. All the tests were performed on the cells from all the six donors. The experiment was performed in triplicate, and the mean value of every sample was used for group comparisons. Comparisons between two experimental groups were performed using the paired t-test. n = 6.