Fig. 1
From: Polymorphisms in SAA alter intrarenal amyloid distribution of AA amyloidosis in cats
Amyloid deposition in the renal medulla in case 1 (a, c, e) and case 4 (b, d, f). Cat. (a, b) Amyloid deposits are highlighted by the Congo red stain (CR). Bars, 100 μm. (c) In case 1, amyloid deposition is primarily observed along the basement membrane of the renal tubules and causes epithelial cell sloughing. Bar, 50 μm. Inset: Amyloid deposits exhibit yellow-green birefringence under polarized light. CR. (d) In case 4, amyloid deposition extends into the renal tubule interstitium. Inset: Amyloid deposits exhibit yellow-green birefringence under polarized light. Bar, 50 μm. CR. (e, f) Amyloid deposits show moderate immunolabeling. Bars, 50 μm. Immunohistochemistry for Pan-SAA.
