Table 5 Stratification analysis.
From: Threshold effect of prognostic nutritional index on mortality in geriatric hip fracture patients
Subgroups | No. of patients | PNI | Inflection point | HR (95%CI) P-value < Inflection point | HR (95%CI) P-value > Inflection point | P for log-likelihood ratio test |
|---|---|---|---|---|---|---|
Age | ||||||
65 < age < = 75 | 608 | 44.78 ± 4.59 | 52.1 | 0.94 (0.90, 0.99) 0.0093 | 1.13 (0.93, 1.37) 0.2083 | 0.153 |
75 < age < = 85 | 1114 | 43.23 ± 4.79 | 49.9 | 0.92 (0.90, 0.95) < 0.0001 | 1.01 (0.95, 1.08) 0.7155 | 0.052 |
85 < age | 393 | 41.49 ± 4.72 | 47.85 | 0.96 (0.92, 1.00) 0.0394 | 1.06 (1.01, 1.12) 0.0325 | 0.023 |
Sex | ||||||
Female | 1443 | 43.65 ± 4.83 | 50.6 | 0.94 (0.92, 0.96) < 0.0001 | 1.07 (1.03, 1.11) 0.0003 | < 0.001 |
Male | 672 | 42.70 ± 4.83 | 45.45 | 0.98 (0.94, 1.01) 0.2165 | 0.73 (0.61, 0.88) 0.0009 | < 0.001 |
aCCI | ||||||
<=4 | 1404 | 43.77 ± 4.73 | 50.35 | 0.95 (0.92, 0.97) 0.0001 | 1.04 (0.99, 1.09) 0.1153 | 0.013 |
> 4 | 711 | 42.53 ± 4.97 | 49.95 | 0.94 (0.91, 0.96) < 0.0001 | 1.01 (0.94, 1.09) 0.8136 | 0.159 |
CHD | ||||||
Yes | 1086 | 43.30 ± 4.94 | 50.3 | 0.94 (0.91, 0.96) < 0.0001 | 1.06 (1.02, 1.11) 0.0078 | < 0.001 |
No | 1029 | 43.41 ± 4.76 | 50.1 | 0.94 (0.91, 0.97) < 0.0001 | 0.98 (0.90, 1.07) 0.6453 | 0.457 |
Arrhythmia | ||||||
Yes | 668 | 43.01 ± 4.70 | 50.05 | 0.94 (0.90, 0.97) 0.0001 | 1.06 (0.94, 1.20) 0.3365 | 0.14 |
No | 1447 | 43.51 ± 4.91 | 50.25 | 0.94 (0.92, 0.97) < 0.0001 | 1.02 (0.98, 1.07) 0.2813 | 0.011 |
Ischemic stroke | ||||||
Yes | 591 | 43.07 ± 4.52 | 47.35 | 0.96 (0.93, 1.00) 0.0600 | 0.63 (0.44, 0.92) 0.0164 | 0.005 |
No | 1524 | 43.46 ± 4.97 | 50.3 | 0.94 (0.92, 0.97) < 0.0001 | 1.05 (1.01, 1.09) 0.0105 | < 0.001 |
Cancer | ||||||
Yes | 59 | 42.19 ± 7.25 | 48.1 | 0.90 (0.82, 0.99) 0.0337 | 1.17 (0.99, 1.38) 0.0601 | 0.042 |
No | 2056 | 43.38 ± 4.76 | 50.3 | 0.94 (0.92, 0.96) < 0.0001 | 1.04 (1.00, 1.09) 0.0495 | 0.002 |
Dementia | ||||||
Yes | 79 | 41.14 ± 6.08 | 36.45 | 1.26 (0.88, 1.82) 0.2108 | 0.99 (0.89, 1.11) 0.8892 | 0.258 |
No | 2036 | 43.44 ± 4.78 | 50.35 | 0.94 (0.92, 0.96) < 0.0001 | 1.05 (1.01, 1.09) 0.0147 | < 0.001 |
Hepatitis | ||||||
Yes | 65 | 42.94 ± 5.31 | 45.2 | 0.98 (0.85, 1.12) 0.7223 | 0.45 (0.22, 0.92) 0.0294 | 0.015 |
No | 2050 | 43.36 ± 4.84 | 50.25 | 0.94 (0.92, 0.96) < 0.0001 | 1.03 (0.99, 1.07) 0.1519 | 0.003 |
Time to admission (h) | ||||||
<=9 | 1064 | 44.21 ± 4.16 | 41.3 | 0.90 (0.84, 0.97) 0.0041 | 0.98 (0.93, 1.02) 0.2844 | 0.115 |
> 9 | 1051 | 42.49 ± 5.32 | 50.15 | 0.94 (0.92, 0.97) < 0.0001 | 1.03 (0.99, 1.08) 0.1432 | 0.009 |
Time to operation (d) | ||||||
<=2 | 491 | 43.58 ± 4.81 | 48.65 | 0.98 (0.93, 1.03) 0.4087 | 0.85 (0.65, 1.12) 0.2435 | 0.271 |
> 2 | 1622 | 43.29 ± 4.86 | 50.1 | 0.93 (0.91, 0.95) < 0.0001 | 1.04 (1.00, 1.08) 0.0511 | < 0.001 |
Urea (mmol/L) | ||||||
<=6.08 | 1040 | 43.75 ± 4.74 | 50.55 | 0.94 (0.92, 0.97) 0.0003 | 1.00 (0.93, 1.08) 0.9309 | 0.213 |
> 6.08 | 1055 | 43.01 ± 4.90 | 49.9 | 0.93 (0.91, 0.96) < 0.0001 | 1.04 (0.99, 1.09) 0.1046 | 0.005 |
