Table 4 Comparison of anesthesia and surgical information in three groups.

From: Remimazolam and propofol combination in ischemic cerebrovascular disease endovascular treatment: a randomized study

 

P(n = 34)

R1(n = 31)

R2(n = 30)

F/H

P

Propofol (mg)

571.3 ± 195.5

378.8 ± 142.7****

290.6 ± 123.3****

22.52

< 0.0001

Remimazolam (mg)

0

15.20(12.20, 19.20)

31.30(26.00, 35.35)

84.50

< 0.0001

Remifentanil (mg)

0.60 ± 0.24

0.51 ± 0.21

0.57 ± 0.20

1.531

0.2225

Fentanyl(mg)

0.20(0.18, 0.20)

0.20(0.10, 0.20)

0.16(0.10, 0.20)

6.102

0.0574

Ephedrine(mg)

15.00(7.50, 20.00)

10.00(5.00, 10.00)**

10.00(5.00, 12.25)

9.462

0.0088

Norepinephrine(mg)

0.54 ± 0.35

0.40 ± 0.26

0.40 ± 0.16

1.369

0.2651

Operation time(min)

106.0 ± 38.09

101.7 ± 44.69

115.9 ± 47.34

0.836

0.4369

Anesthesia time(min)

141.0(128.5, 176)

128.0(106.0, 156)

150.0(118.5, 172)

2.542

0.2808

BIS

47.5(40.25, 52.00)

47.50(41.75, 52.50)

41.00(40.00, 49.00)

3.272

0.1948

Urine volume(ml)

511.6 ± 386.4

603.1 ± 336.9

267.8 ± 330.4

2.559

0.0897

Infusion volume(ml)

1080(1040, 1100)

1000(600.0, 1220)

1000(540.0, 1290)

1.188

0.5522

Temperature (℃)

36.5(36.4, 36.6)

36.5(36.4, 36.6)

36.5(36.4, 36.6)

0.204

0.9208

Recovery time(min)

33.00(27.00, 57.50)

31.00(27.00, 54.00)

23.00(14.50, 33.00)*

12.99

0.0015

Extubation time(min)

48.00(35.00, 63.00)

38.00(30.00, 59.00)

30.50(24.50, 49.50)*

8.000

0.0183

PACU stay time(min)

112.0(88.0, 155.0)

105.0(80.0, 140.0)

100.5(85.25, 113.8)

3.273

0.1947

Postoperative hospital stay(Day)

3.00(3.00, 6.00)

3.00(3.00, 4.00)

3.00(2.75, 6.00)

1.377

0.5022

  1. Note: Data are presented as the mean ± SD, number of patients (percentage), or median (inter-quartile range).
  2. Abbreviations: BIS, fluctuation of mean blood pressure; PACU, Postanesthesia care unit. *P < 0.05, **P < 0.01, ****P < 0.0001, significant as compared to the P group; P < 0.0001, significant as compared to the R1 group.