Fig. 3
From: Rare genetic variants and severe COVID-19 in previously healthy admixed Latin American adults

Strategy for prioritizing functional variants in COVID-19-BR cases. The numbers shown at each stage represent the remaining variants after applying the corresponding filters. Abbreviations – 1KGP: 1000 Genomes Project, Phase 3; CADD: Combined Annotation-Dependent Depletion algorithm; GDI: Gene Damage Index; gnomAD: Genome Aggregation Database version 4.1; MAF: minor allele frequency.