Table 6 Multivariate Cox regression: factors associated with hospital and ICU length of stay.
Variables | Dependent variable = hospital LOS | Dependent variable = ICU LOS | ||||||
---|---|---|---|---|---|---|---|---|
Wald | SE | p-value | OR (95% CI) | Wald | SE | pvalue | OR (95% CI) | |
Age | 1.898 | 0.005 | 0.168 | 0.994 (0.985–1.003) | 3.386 | 0.004 | 0.066 | 0.992 (0.983–1.001) |
Gender | 1.177 | 0.151 | 0.278 | 1.178 (0.876–1.585) | 0.232 | 0.150 | 0.630 | 1.075 (0.801–1.444) |
BMI | 1.216 | 0.011 | 0.270 | 0.988 (0.967–1.010) | 1.655 | 0.011 | 0.198 | 0.986 (0.965–1.008) |
Corticosteroids during ICU stay | 0.889 | 0.153 | 0.346 | 1.156 (0.856–1.561) | 0.591 | 0.157 | 0.442 | 0.886 (0.651–1.206) |
Tocilizumab | 4.920 | 0.148 | 0.027** | 0.720 (0.539–0.962) | 0.774 | 0.153 | 0.379 | 0.874 (0.648–1.179) |
Mean BP (mmHg) | 0.671 | 0.004 | 0.413 | 1.003 (0.996–1.011) | 0.108 | 0.004 | 0.742 | 1.001 (0.994–1.009) |
Heart rate (bpm) | 0.510 | 0.004 | 0.475 | 1.003 (0.995–1.010) | 0.613 | 0.004 | 0.434 | 1.003 (0.995–1.011) |
Respiratory rate | 0.641 | 0.011 | 0.423 | 0.991 (0.971–1.013) | 0.000 | 0.011 | 0.995 | 1.000 (0.979–1.021) |
Oxygen saturation (%) | 0.001 | 0.008 | 0.971 | 1.000 (0.985–1.016) | 2.125 | 0.008 | 0.145 | 0.988 (0.973–1.004) |
Glasgow Coma Score | 0.632 | 0.029 | 0.427 | 0.977 (0.924–1.034) | 0.469 | 0.031 | 0.493 | 0.979 (0.922–1.040) |
Current smoker | 5.999 | 0.143 | 0.014** | 0.705 (0.533–0.933) | 8.125 | 0.143 | 0.004** | 0.665 (0.503–0.880) |
Diabetes mellitus | 0.085 | 0.296 | 0.771 | 1.090 (0.610–1.947) | 0.542 | 0.303 | 0.461 | 1.250 (0.690–2.266) |
Hypertension | 1.930 | 0.155 | 0.165 | 1.240 (0.916–1.678) | 1.988 | 0.157 | 0.159 | 1.247 (0.918–1.695) |
Ischemic heart disease | 1.263 | 0.161 | 0.261 | 1.198 (0.874–1.642) | 1.090 | 0.161 | 0.297 | 1.184 (0.863–1.624) |
Heart failure (EF < 50%) | 2.432 | 0.241 | 0.119 | 0.687 (0.428–1.101) | 1.547 | 0.245 | 0.214 | 0.738 (0.457–1.191) |
Chronic lung disease | 0.054 | 0.417 | 0.817 | 1.101 (0.486–2.494) | 0.152 | 0.438 | 0.697 | 0.843 (0.357–1.990) |
COPD | 3.053 | 0.417 | 0.081 | 0.482 (0.213–1.093) | 1.909 | 0.428 | 0.167 | 0.554 (0.239–1.281) |
Bronchial asthma | 1.031 | 0.541 | 0.310 | 1.733 (0.600–5.008) | 0.157 | 0.565 | 0.692 | 1.251 (0.413–3.784) |
Chronic liver disease | 2.209 | 0.235 | 0.137 | 1.417 (0.895–2.245) | 1.404 | 0.230 | 0.236 | 1.313 (0.837–2.058) |
Hemoglobinopathy | 0.062 | 0.540 | 0.803 | 1.144 (0.397–3.297) | 0.352 | 0.525 | 0.553 | 0.732 (0.262–2.051) |
CKD (GFR < 60 ml/min) | 3.189 | 0.606 | 0.074 | 0.339 (0.103–1.111) | 4.102 | 0.614 | 0.043** | 0.288 (0.087–0.961) |
Dialysis | 2.485 | 0.383 | 0.115 | 1.828 (0.863–3.872) | 0.297 | 0.397 | 0.586 | 1.242 (0.570–2.706) |
Transplant (SOT/BMT) | 0.901 | 0.373 | 0.343 | 0.702 (0.337–1.459) | 0.023 | 0.388 | 0.879 | 0.943 (0.441–2.017) |
Immunocompromised status | 0.232 | 0.620 | 0.630 | 0.742 (0.220–2.501) | 1.404 | 0.649 | 0.236 | 0.464 (0.130–1.653) |
Chronic hematologic disease | 0.553 | 0.483 | 0.457 | 0.698 (0.271–1.800) | 0.568 | 0.428 | 0.451 | 1.381 (0.597–3.194) |
HIV/AIDS | 0.027 | 0.735 | 0.869 | 0.886 (0.210–3.740) | 1.504 | 0.731 | 0.220 | 0.408 (0.097–1.710) |
Recent surgery (within 30 days) | 0.891 | 0.482 | 0.345 | 1.576 (0.613–4.052) | 0.120 | 0.449 | 0.729 | 1.168 (0.485–2.816) |