Table 7 Overall patients’ outcomes.

From: Tocilizumab as a targeted immunomodulatory therapy in the management of severe respiratory illnesses: a multicenter cohort study of COVID-19 patients

Characteristics

All patients

Tocilizumab (n = 426, 29.0%)

Non-tocilizumab (n = 1044, 71.0%)

Adjusted OR (95% CI)

P-value

Hospital mortality

   

0.75 (0.63–0.89)

 < 0.001**

 Dead

Overall death 614 (41%)

157 (36.9%)

457 (43.8%)

  

 Alive

269 (63.1%)

587 (56.2%)

  

Length of stay in ICU in days

9 (5–16)

12 (7–21)

8 (4–15)

0.68 (0.57–0.83)

 < 0.001***

Length of stay in the Hospital in days

15 (9–124)

18 (12–30)

14 (8–23)

0.72 (0.57–0.91)

0.003**

ICU mortality

   

3.4 days (2.1–4.8)

 < 0.001***

 Dead

601 (40.9)

150(35.2.9%)

452 (43.3%)

  

 Alive

 

276 (64.8%)

592 (56.7%)

  

Number of patients who required mechanical ventilation

   

6 days (1.2–4.0)

 < 0.001***

 MV

778 (52.4%)

210 (49.3%)

482 (46.2%)

  

 Didn’t require mechanical ventilation

 

216 (50.7%)

562 (53.8%)

  

Candidemia

37 (3.4)

13 (3.5%)

24 (3.3%)

Bactermia

263 (24.5)

82 (21.9)

181 (26)

Complication, bacteremia without candidemia

225 (21)

69 (18.4)

156 (22.4)

Complications, positive respiratory culture

   

 Yes

 

32 (7.5%)

57 (5.5%)

  

 No

 

394 (92.5%)

987 (94.5%)

  
  1. **Significant, if p-value < 0.05 and *** Highly Significant, if p-value < 0.001.