Fig. 4
Effect of MIR155HG on cisplatin sensitivity of cervical cancer cells. (A) Growth inhibition of Hela cells was observed at different concentrations of cisplatin by CCK-8 method (mean ± STD, n = 5). (B) Growth inhibition of Hela cells was reduced after overexpression of MIR155HG at different concentrations of cisplatin. (C) Plate clonality assays was used to measure the impact of cisplatin to cell clonality in Hela cells after overexpression of MIR155HG. (D) Flow cytometry was adopted to examine apoptotic rate in Hela cells with cisplatin after overexpression of MIR155HG. (E). Effect of cisplatin on proliferation of Hela cells after overexpression of MIR155HG at different time. N = 3 for C-D, and N = 5 for A-B and E; One-way ANOVA test, * p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001, **** p-value < 0.0001; ns, non-significant.
