Fig. 1
From: TFF3 initiates gastric intestinal metaplasia by activating JAK2 and STAT3 under high salt conditions
Construction of the gastric mucosal epithelial cell intestinalization model. (A) Expression levels of CDX2, VIL1, KLF4, and MUC2 after 24 h treatment with different NaCl concentrations (20, 40, 80, and 100 mM) in GES-1 cells; (B) Expression levels after treatment with 80 mM NaCl for varying durations (4 h, 8 h, 12 h, 24 h, and 48 h); (C) Expression levels after 24 h treatment with different concentrations of CDCA (50, 62.5, 75, 87.5, and 100 µM); (D) Expression levels after treatment with 100 µM CDCA for varying durations (4 h, 8 h, 12 h, and 24 h). CDCA Chenodeoxycholic acid, NC Negative control, ns not significant; *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.
