Table 1 Differences in demographic data and clinical information between PSD and non-PSD groups.
Variables | Total (N = 507) | PSD (n = 158) | Non-PSD (n = 349) | P-value |
|---|---|---|---|---|
General information | ||||
Gender (Men), n (%) | 310(61.14) | 85(53.80) | 225(64.47) | 0.022 |
Age, years, mean(± SD) | 63.84 ± 9.36 | 64.03 ± 9.36 | 63.76 ± 9.36 | 0.770 |
Educational levels, n(%) | 0.021 | |||
Primary school or below | 159(31.36) | 50(31.65) | 109(31.23) | |
Junior high school or senior high school | 127(25.05) | 51(32.28) | 76(21.78) | |
University or above | 221(43.59) | 57(36.08) | 164(46.99) | |
Marital status, n(%) | < 0.001 | |||
Married | 473(93.29) | 137(86.71) | 336(96.28) | |
Unmarried, divorced or widowed | 34(6.71) | 21(13.29) | 13(3.73) | |
Type of work, n(%) | 0.201 | |||
Manual labor | 202(39.84) | 72(45.57) | 130(37.25) | |
Mental labor | 170(33.53) | 49(31.01) | 121(34.67) | |
Both manual and mental labor | 135(26.63) | 37(23.42) | 98(28.08) | |
Heart rate, times/min, mean(± SD) | 75.99 ± 11.15 | 76.49 ± 11.45 | 75.76 ± 11.01 | 0.499 |
SBP, mmHg, mean(± SD) | 145.77 ± 20.45 | 147.55 ± 21.34 | 144.97 ± 19.98 | 0.188 |
DBP, mmHg, mean(± SD) | 86.36 ± 13.36 | 86.71 ± 14.93 | 86.20 ± 12.58 | 0.694 |
Smoking, n(%) | 125(24.66) | 48(30.38) | 77(22.06) | 0.044 |
Drinking, n(%) | 116(22.88) | 44(27.85) | 72(20.63) | 0.073 |
Hypertension, n(%) | 376(74.16) | 126(79.75) | 250(71.63) | 0.053 |
Coronary heart disease, n(%) | 102(20.12) | 31(19.62) | 71(20.34) | 0.851 |
Diabetes, n(%) | 231(45.56) | 83(52.53) | 148(42.41) | 0.034 |
Hyperlipidemia, n(%) | 350(69.03) | 119(75.32) | 231(66.19) | 0.040 |
Atrial fibrillation, n(%) | 31(6.11) | 17(10.76) | 14(4.01) | 0.003 |
Family history of depression, n(%) | 66(13.02) | 44(12.61) | 22(13.92) | 0.683 |
Imaging test parameters | ||||
Focal location | ||||
Frontal lobe lesion, n(%) | 151(29.78) | 74(46.84) | 77(22.06) | < 0.001 |
Parietal lobe lesion, n(%) | 66(13.02) | 24(15.19) | 42(12.03) | 0.328 |
Occipital lobe lesion, n(%) | 63(12.43) | 25(15.82) | 38(10.89) | 0.119 |
Temporal lobe lesion, n(%) | 64(12.62) | 30(18.99) | 34(9.74) | 0.004 |
Basal ganglia lesion, n(%) | 233(45.96) | 87(55.06) | 146(41.83) | 0.006 |
Paraventricular lesion, n(%) | 37(7.298) | 10(6.329) | 27(7.736) | 0.573 |
Brain lesion, n(%) | 130(25.64) | 38(24.05) | 92(26.36) | 0.581 |
Cerebellar lesion, n(%) | 51(10.06) | 21(13.29) | 30(8.60) | 0.104 |
Thalamic lesion, n(%) | 74(14.60) | 20(12.66) | 54(15.47) | 0.406 |
Pontine lesion, n(%) | 36(7.10) | 8(5.06) | 28(8.02) | 0.229 |
Brain stem lesion, n(%) | 57(11.24) | 21(13.29) | 36(10.32) | 0.326 |
Radiative crown lesion, n(%) | 145(28.60) | 47(29.75) | 98(28.08) | 0.701 |
Hemioval central lesion, n(%) | 35(6.90) | 13(8.23) | 22(6.30) | 0.429 |
Number of lesions, n(%) | < 0.001 | |||
Single | 104(20.51) | 15(9.49) | 89(25.50) | |
Multiple | 403(79.49) | 143(90.51) | 260(74.50) | |
Focal side, n(%) | 0.363 | |||
Left | 162(31.95) | 48(30.38) | 114(32.67) | |
Right | 101(19.92) | 27(17.09) | 74(21.20) | |
Left and right | 244(48.13) | 83(52.53) | 161(46.13) | |
Laboratory test parameters | ||||
WBC, 109/L, mean(± SD) | 6.65 ± 2.28 | 7.26 ± 2.75 | 6.38 ± 1.97 | < 0.001 |
ANC, 109/L, mean(± SD) | 5.49 ± 8.46 | 5.33 ± 5.06 | 5.55 ± 9.61 | 0.787 |
RBC, 1012/L, mean(± SD) | 4.41 ± 0.53 | 4.42 ± 0.53 | 4.40 ± 0.53 | 0.774 |
HGB, g/L, mean(± SD) | 132.38 ± 16.50 | 130.37 ± 17.23 | 133.28 ± 16.08 | 0.066 |
HCT, mean(± SD) | 40.15 ± 4.96 | 39.60 ± 5.65 | 40.39 ± 4.59 | 0.122 |
RDW, fL, mean(± SD) | 43.32 ± 4.67 | 44.24 ± 5.25 | 42.90 ± 4.32 | 0.003 |
PLT, 109/L, mean(± SD) | 222.32 ± 75.09 | 220.67 ± 92.78 | 223.07 ± 65.52 | 0.770 |
PDW, fL, M(P25, P75) | 11.50(10.50, 13.00) | 11.30(10.40, 12.90) | 11.60(10.50, 13.10) | 0.417 |
ALT, U/L, M(P25, P75) | 17.00(12.00, 25.00) | 16.00(11.00, 23.00) | 17.00(13.00, 26.00) | 0.095 |
AST, U/L, M(P25, P75) | 18(16, 23) | 18(15, 25) | 18(16, 23) | 0.961 |
ALB[g/L, mean(± SD)] | 37.89 ± 4.00 | 36.61 ± 4.41 | 38.47 ± 3.66 | < 0.001 |
GLB, g/L, mean(± SD) | 26.08 ± 3.98 | 25.93 ± 4.01 | 26.14 ± 3.97 | 0.566 |
PAB, mg/L, mean(± SD) | 231.80 ± 57.63 | 222.39 ± 61.43 | 236.06 ± 55.29 | 0.013 |
SCr, umol/L, M(P25, P75) | 55(46, 68) | 54(46, 63) | 56(47, 71) | 0.036 |
SUA, umol/L, M(P25, P75) | 301(238, 367) | 281(223, 358) | 305(246, 368) | 0.090 |
FBG, mmol/L, mean(± SD) | 6.50 ± 1.96 | 6.78 ± 2.23 | 6.38 ± 1.81 | 0.030 |
TG, mmol/L, M(P25, P75) | 1.20(0.89, 1.70) | 1.07(0.79, 1.87) | 1.22(0.92, 1.65) | 0.338 |
TC, mmol/L, mean(± SD) | 4.15 ± 1.40 | 4.06 ± 1.24 | 4.20 ± 1.47 | 0.311 |
HDL-C, mmol/L, mean(± SD) | 1.06 ± 0.28 | 1.03 ± 0.26 | 1.07 ± 0.29 | 0.138 |
LDL-C, mmol/L, mean(± SD) | 2.44 ± 0.98 | 2.49 ± 1.04 | 2.42 ± 0.95 | 0.430 |
APOA1, g/L, mean(± SD) | 1.29 ± 0.27 | 1.23 ± 0.24 | 1.31 ± 0.29 | 0.001 |
APOB, g/L, mean(± SD) | 0.82 ± 0.30 | 0.83 ± 0.30 | 0.81 ± 0.30 | 0.530 |
Lp(a), mg/L, M(P25, P75) | 18.80(11.20, 39.70) | 19.20(13.20, 41.90) | 18.30(10.30, 38.00) | 0.197 |
Scale evaluation parameter | ||||
NIHSS score, points, mean(± SD) | 3.82 ± 3.90 | 5.99 ± 4.86 | 2.83 ± 2.88 | < 0.001 |
PSQI score, points, mean(± SD) | 6.98 ± 6.30 | 11.99 ± 5.53 | 4.71 ± 5.23 | < 0.001 |
MMSE score, points, mean(± SD) | 25.77 ± 3.92 | 23.84 ± 3.92 | 23.84 ± 3.92 | < 0.001 |
Barthel score, points, mean(± SD) | 71.30 ± 15.80 | 69.43 ± 17.13 | 72.15 ± 15.09 | 0.088 |
APGAR score, points, mean(± SD) | 6.91 ± 1.48 | 6.73 ± 2.15 | 6.99 ± 1.03 | 0.164 |
Medication information, n(%) | ||||
Antihypertensive drugs, n(%) | 329(64.89) | 107(67.72) | 222(63.61) | 0.369 |
Lipid-lowering drugs, n(%) | 131(25.84) | 42(26.58) | 89(25.50) | 0.797 |
Hypoglycemic drugs, n(%) | 183(36.10) | 62(39.24) | 121(34.67) | 0.321 |
