Fig. 1

Variation in the integrated HIV-DNA reservoir in the study groups. The HIV-DNA reservoir was determined in PBMCs and values were normalized according to CD4 percentage data. Values below 1 copy of integrated HIV-DNA/million PBMCs were considered as 1. Statistical analysis: mixed linear regression analysis (** p < 0.01; *** p < 0.001). The median CD4 counts were: (a) 96 and 367 at pre-ART in MVC-Initiation and non-MVC-Initiation groups, respectively; and 279 pre-MVC in the MVC-switch group; (b) 468 and 668 at post-ART in MVC-Initiation and non-MVC-Initiation groups, respectively; and 515 post-MVC in the MVC-switch group.