Fig. 2 | Scientific Reports

Fig. 2

From: Impact of the initial administration of an antiretroviral drug with latency reversal properties on the HIV reservoir size

Fig. 2

Variation in the IPDA-total, IPDA-defective and IPDA-intact HIV-DNA reservoir in the study groups. The HIV proviral DNA levels: (A) IPDA-total, (B) IPDA-defective and (C) IPDA-intact, were determined in PBMCs and values were normalized according to CD4 percentage data. Values below 1 copy of HIV-DNA/million PBMCs were considered as 1. Statistics: mixed linear regression analysis (* p < 0.05; *** p < 0.001, n.s.: not significant). The median CD4 counts were: a) 92 and 369 at pre-ART in MVC-Initiation and non-MVC-Initiation groups, respectively; and 279 pre-MVC in the MVC-switch group; b) 486 and 677 at post-ART in MVC-Initiation and non-MVC-Initiation groups, respectively; and 515 post-MVC in the MVC-switch group.

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