Table 6 Adverse events of eptinezumab group versus placebo group on the basis of different eptinezumab doses subgroups.

From: Comprehensive safety analysis of adverse events associated with eptinezumab in migraine treatment

Subgroups

Number of studies

Number of events/participants

I2(%)

Risk ratio(95%CI)

P

Eptinezumab group

Placebo group

1000 mg

1

46/81

43/82

N/A

1.08 (0.82–1.43)

0.58

300 mg

4

508/989

490/1007

0

1.05 (0.97–1.15)

0.23

100 mg

5

519/1238

515/1249

0

1.01 (0.93–1.11)

0.75

30 mg

2

184/341

200/343

35

0.93 (0.81–1.06)

0.26

10 mg

1

74/130

68/121

N/A

1.01 (0.82–1.26)

0.91

  1. N/A not applicable, CI confidence interval.